Kelly G - Search Results

1

Genome-scale clustered regularly interspaced short palindromic repeats screen identifies nucleotide metabolism as an actionable therapeutic vulnerability in diffuse large B-cell lymphoma.

Davies N, Francis T, Oldreive C, Azam M, Wilson J, Byrd PJ, Burley M, Sharma-Oates A, Keane P, Alatawi S, Higgs MR, Rudzki Z, Ibrahim M, Perry T, Agathanggelou A, Hewitt AM, Smith E, Bonifer C, O'Connor M, Forment JV, Murray PG, Fennell E, Kelly G, Chang C, Stewart GS, Stankovic T, Kwok M, Taylor AM. Davies N, et al. Among authors: kelly g. Haematologica. 2024 Dec 1;109(12):3989-4006. doi: 10.3324/haematol.2023.284404. Haematologica. 2024. PMID: 38841800 Free PMC article.

2

Humanized Mcl-1 mice enable accurate preclinical evaluation of MCL-1 inhibitors destined for clinical use.

Brennan MS, Chang C, Tai L, Lessene G, Strasser A, Dewson G, Kelly GL, Herold MJ. Brennan MS, et al. Among authors: kelly gl. Blood. 2018 Oct 11;132(15):1573-1583. doi: 10.1182/blood-2018-06-859405. Epub 2018 Aug 23. Blood. 2018. PMID: 30139826 Free article.

3

BCL-W is dispensable for the sustained survival of select Burkitt lymphoma and diffuse large B-cell lymphoma cell lines.

Diepstraten ST, Chang C, Tai L, Gong JN, Lan P, Dowell AC, Taylor GS, Strasser A, Kelly GL. Diepstraten ST, et al. Blood Adv. 2020 Jan 28;4(2):356-366. doi: 10.1182/bloodadvances.2019000541. Blood Adv. 2020. PMID: 31985804 Free PMC article.

4

Flow cytometric single cell-based assay to simultaneously detect cell death, cell cycling, DNA content and cell senescence.

Lieschke E, Wang Z, Chang C, Weeden CE, Kelly GL, Strasser A. Lieschke E, et al. Cell Death Differ. 2022 May;29(5):1004-1012. doi: 10.1038/s41418-022-00964-7. Epub 2022 Mar 9. Cell Death Differ. 2022. PMID: 35264779 Free PMC article.

5

BCL-W makes only minor contributions to MYC-driven lymphoma development.

Diepstraten ST, La Marca JE, Chang C, Young S, Strasser A, Kelly GL. Diepstraten ST, et al. Oncogene. 2023 Sep;42(37):2776-2781. doi: 10.1038/s41388-023-02804-5. Epub 2023 Aug 11. Oncogene. 2023. PMID: 37567974 Free PMC article.

6

Down-regulation of the TGF-beta target gene, PTPRK, by the Epstein-Barr virus encoded EBNA1 contributes to the growth and survival of Hodgkin lymphoma cells.

Flavell JR, Baumforth KR, Wood VH, Davies GL, Wei W, Reynolds GM, Morgan S, Boyce A, Kelly GL, Young LS, Murray PG. Flavell JR, et al. Among authors: kelly gl. Blood. 2008 Jan 1;111(1):292-301. doi: 10.1182/blood-2006-11-059881. Epub 2007 Aug 24. Blood. 2008. PMID: 17720884 Free article.

7

ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress.

Liu R, King A, Hoch NC, Chang C, Kelly GL, Deans AJ, Heierhorst J. Liu R, et al. DNA Repair (Amst). 2017 Sep;57:29-34. doi: 10.1016/j.dnarep.2017.06.022. Epub 2017 Jun 17. DNA Repair (Amst). 2017. PMID: 28648892 Free PMC article.

8

Coordinated repression of BIM and PUMA by Epstein-Barr virus latent genes maintains the survival of Burkitt lymphoma cells.

Fitzsimmons L, Boyce AJ, Wei W, Chang C, Croom-Carter D, Tierney RJ, Herold MJ, Bell AI, Strasser A, Kelly GL, Rowe M. Fitzsimmons L, et al. Cell Death Differ. 2018 Feb;25(2):241-254. doi: 10.1038/cdd.2017.150. Epub 2017 Sep 29. Cell Death Differ. 2018. PMID: 28960205 Free PMC article.

9

EBV BCL-2 homologue BHRF1 drives chemoresistance and lymphomagenesis by inhibiting multiple cellular pro-apoptotic proteins.

Fitzsimmons L, Cartlidge R, Chang C, Sejic N, Galbraith LCA, Suraweera CD, Croom-Carter D, Dewson G, Tierney RJ, Bell AI, Shannon-Lowe C, Herold MJ, Rickinson AB, Colman PM, Huang DCS, Strasser A, Kvansakul M, Rowe M, Kelly GL. Fitzsimmons L, et al. Among authors: kelly gl. Cell Death Differ. 2020 May;27(5):1554-1568. doi: 10.1038/s41418-019-0435-1. Epub 2019 Oct 23. Cell Death Differ. 2020. PMID: 31645677 Free PMC article.

10

Loss of TRP53 reduces but does not overcome dependency of lymphoma cells on MCL-1.

Aubrey BJ, Brennan MS, Diepstraten ST, Wang Z, Chang C, Herold MJ, Strasser A, Kelly GL. Aubrey BJ, et al. Cell Death Differ. 2022 May;29(5):1074-1076. doi: 10.1038/s41418-022-00946-9. Epub 2022 Jan 28. Cell Death Differ. 2022. PMID: 35091693 Free PMC article. No abstract available.

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