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Soluble epoxide hydrolase is a therapeutic target for acute inflammation.
Schmelzer KR, Kubala L, Newman JW, Kim IH, Eiserich JP, Hammock BD. Schmelzer KR, et al. Among authors: kubala l. Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9772-7. doi: 10.1073/pnas.0503279102. Epub 2005 Jun 30. Proc Natl Acad Sci U S A. 2005. PMID: 15994227 Free PMC article.
Heparins increase endothelial nitric oxide bioavailability by liberating vessel-immobilized myeloperoxidase.
Baldus S, Rudolph V, Roiss M, Ito WD, Rudolph TK, Eiserich JP, Sydow K, Lau D, Szöcs K, Klinke A, Kubala L, Berglund L, Schrepfer S, Deuse T, Haddad M, Risius T, Klemm H, Reichenspurner HC, Meinertz T, Heitzer T. Baldus S, et al. Among authors: kubala l. Circulation. 2006 Apr 18;113(15):1871-8. doi: 10.1161/CIRCULATIONAHA.105.590083. Epub 2006 Apr 10. Circulation. 2006. PMID: 16606792
Pathogenic cycle between the endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine and the leukocyte-derived hemoprotein myeloperoxidase.
von Leitner EC, Klinke A, Atzler D, Slocum JL, Lund N, Kielstein JT, Maas R, Schmidt-Haupt R, Pekarova M, Hellwinkel O, Tsikas D, D'Alecy LG, Lau D, Willems S, Kubala L, Ehmke H, Meinertz T, Blankenberg S, Schwedhelm E, Gadegbeku CA, Böger RH, Baldus S, Sydow K. von Leitner EC, et al. Among authors: kubala l. Circulation. 2011 Dec 13;124(24):2735-45. doi: 10.1161/CIRCULATIONAHA.111.060541. Epub 2011 Nov 14. Circulation. 2011. PMID: 22082678
159 results