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Page 1
Macrophages are activated toward phagocytic lymphoma cell clearance by pentose phosphate pathway inhibition.
Beielstein AC, Izquierdo E, Blakemore S, Nickel N, Michalik M, Chawan S, Brinker R, Bartel HH, Vorholt D, Albert L, Nolte JL, Linke R, Costa Picossi CR, Sáiz J, Picard F, Florin A, Meinel J, Büttner R, Diefenhardt P, Brähler S, Villaseñor A, Winkels H, Hallek M, Krüger M, Barbas C, Pallasch CP. Beielstein AC, et al. Among authors: vorholt d. Cell Rep Med. 2024 Dec 17;5(12):101830. doi: 10.1016/j.xcrm.2024.101830. Epub 2024 Nov 26. Cell Rep Med. 2024. PMID: 39603243 Free article.
Multinational proficiency tests for EGFR exon 20 insertions reveal that the assay design matters.
Ihle MA, Heydt C, Schultheis AM, Stöhr R, Haller F, Herold S, Aust D, Dietmaier W, Evert M, Eszlinger M, Haak A, Laßmann S, Vorholt D, Breitenbücher F, Werner M, Streubel A, Mairinger T, Grassow-Narlik M, Merkelbach-Bruse S. Ihle MA, et al. Among authors: vorholt d. Sci Rep. 2024 Jun 6;14(1):13069. doi: 10.1038/s41598-024-63821-2. Sci Rep. 2024. PMID: 38844820 Free PMC article.
Extracellular vesicles and PD-L1 suppress macrophages, inducing therapy resistance in TP53-deficient B-cell malignancies.
Izquierdo E, Vorholt D, Blakemore S, Sackey B, Nolte JL, Barbarino V, Schmitz J, Nickel N, Bachurski D, Lobastova L, Nikolic M, Michalik M, Brinker R, Merkel O, Franitza M, Georgomanolis T, Neuhaus R, Koch M, Nasada N, Knittel G, Chapuy B, Ludwig N, Meese E, Frenzel L, Reinhardt HC, Peifer M, Rebollido-Rios R, Bruns H, Krüger M, Hallek M, Pallasch CP. Izquierdo E, et al. Among authors: vorholt d. Blood. 2022 Jun 23;139(25):3617-3629. doi: 10.1182/blood.2021014007. Blood. 2022. PMID: 35344582 Free article.
Inflammatory Pre-Conditioning of Adipose-Derived Stem Cells with Cerebrospinal Fluid from Traumatic Brain Injury Patients Alters the Immunomodulatory Potential of ADSC Secretomes.
Üçal M, Maurer C, Etschmaier V, Hamberger D, Grünbacher G, Tögl L, Roosen MJ, Molcanyi M, Vorholt D, Hatay FF, Hescheler J, Pallasch C, Schäfer U, Patz S. Üçal M, et al. Among authors: vorholt d. J Neurotrauma. 2021 Aug 15;38(16):2311-2322. doi: 10.1089/neu.2020.7017. Epub 2021 Mar 4. J Neurotrauma. 2021. PMID: 33514282
Macrophage-Mediated Antibody Dependent Effector Function in Aggressive B-Cell Lymphoma Treatment is Enhanced by Ibrutinib via Inhibition of JAK2.
Barbarino V, Henschke S, Blakemore SJ, Izquierdo E, Michalik M, Nickel N, Möllenkotte I, Vorholt D, Müller L, Brinker R, Fedorchenko O, Mikhael N, Seeger-Nukpezah T, Hallek M, Pallasch CP. Barbarino V, et al. Among authors: vorholt d. Cancers (Basel). 2020 Aug 15;12(8):2303. doi: 10.3390/cancers12082303. Cancers (Basel). 2020. PMID: 32824276 Free PMC article.
Sensitizing protective tumor microenvironments to antibody-mediated therapy.
Pallasch CP, Leskov I, Braun CJ, Vorholt D, Drake A, Soto-Feliciano YM, Bent EH, Schwamb J, Iliopoulou B, Kutsch N, van Rooijen N, Frenzel LP, Wendtner CM, Heukamp L, Kreuzer KA, Hallek M, Chen J, Hemann MT. Pallasch CP, et al. Among authors: vorholt d. Cell. 2014 Jan 30;156(3):590-602. doi: 10.1016/j.cell.2013.12.041. Cell. 2014. PMID: 24485462 Free PMC article.
High-resolution transcriptome of human macrophages.
Beyer M, Mallmann MR, Xue J, Staratschek-Jox A, Vorholt D, Krebs W, Sommer D, Sander J, Mertens C, Nino-Castro A, Schmidt SV, Schultze JL. Beyer M, et al. Among authors: vorholt d. PLoS One. 2012;7(9):e45466. doi: 10.1371/journal.pone.0045466. Epub 2012 Sep 21. PLoS One. 2012. PMID: 23029029 Free PMC article.