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Activin A directly impairs human cardiomyocyte contractile function indicating a potential role in heart failure development.
MacDonnell S, Megna J, Ruan Q, Zhu O, Halasz G, Jasewicz D, Powers K, E H, Del Pilar Molina-Portela M, Jin X, Zhang D, Torello J, Feric NT, Graziano MP, Shekhar A, Dunn ME, Glass D, Morton L. MacDonnell S, et al. Among authors: graziano mp. Front Cardiovasc Med. 2022 Nov 10;9:1038114. doi: 10.3389/fcvm.2022.1038114. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 36440002 Free PMC article.
Opportunities and challenges for use of minipigs in nonclinical pharmaceutical development: Results of a follow-up IQ DruSafe survey.
Clarke DO, Datta K, French K, Leach MW, Olaharski D, Mohr S, Strein D, Bussiere J, Feyen B, Gauthier BE, Graziano M, Harding J, Hershman K, Jacob B, Ji S, Lange R, Salian-Mehta S, Sayers B, Thomas N, Flandre T. Clarke DO, et al. Among authors: graziano m. Regul Toxicol Pharmacol. 2024 Dec;154:105729. doi: 10.1016/j.yrtph.2024.105729. Epub 2024 Oct 30. Regul Toxicol Pharmacol. 2024. PMID: 39481797 Free article.
Electrical stimulation of biofidelic engineered muscle enhances myotube size, force, fatigue resistance, and induces a fast-to-slow-phenotype shift.
Pallotta I, Stec MJ, Schriver B, Golann DR, Considine K, Su Q, Barahona V, Napolitano JE, Stanley S, Garcia M, Feric NT, Durney KM, Aschar-Sobbi R, Bays N, Shavlakadze T, Graziano MP. Pallotta I, et al. Among authors: graziano mp. Physiol Rep. 2024 Oct;12(19):e70051. doi: 10.14814/phy2.70051. Physiol Rep. 2024. PMID: 39384537 Free PMC article.
Single-Molecule Mechanoresistivity by Intermetallic Bonding.
Sil A, Spano CE, Chelli Y, Higgins SJ, Sangtarash S, Piccinini G, Graziano M, Nichols RJ, Sadeghi H, Vezzoli A. Sil A, et al. Among authors: graziano m. Angew Chem Int Ed Engl. 2024 Sep 26:e202418062. doi: 10.1002/anie.202418062. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 39324416
374 results