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Page 1
Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma.
El-Hachem N, Leclercq M, Susaeta Ruiz M, Vanleyssem R, Shostak K, Körner PR, Capron C, Martin-Morales L, Roncarati P, Lavergne A, Blomme A, Turchetto S, Goffin E, Thandapani P, Tarassov I, Nguyen L, Pirotte B, Chariot A, Marine JC, Herfs M, Rapino F, Agami R, Close P. El-Hachem N, et al. Among authors: rapino f. Nat Cell Biol. 2024 Jul;26(7):1154-1164. doi: 10.1038/s41556-024-01439-2. Epub 2024 Jun 7. Nat Cell Biol. 2024. PMID: 38849541 Free PMC article.
Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine.
Ladang A, Rapino F, Heukamp LC, Tharun L, Shostak K, Hermand D, Delaunay S, Klevernic I, Jiang Z, Jacques N, Jamart D, Migeot V, Florin A, Göktuna S, Malgrange B, Sansom OJ, Nguyen L, Büttner R, Close P, Chariot A. Ladang A, et al. Among authors: rapino f. J Exp Med. 2015 Nov 16;212(12):2057-75. doi: 10.1084/jem.20142288. Epub 2015 Nov 2. J Exp Med. 2015. PMID: 26527802 Free PMC article.
Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer.
Delaunay S, Rapino F, Tharun L, Zhou Z, Heukamp L, Termathe M, Shostak K, Klevernic I, Florin A, Desmecht H, Desmet CJ, Nguyen L, Leidel SA, Willis AE, Büttner R, Chariot A, Close P. Delaunay S, et al. Among authors: rapino f. J Exp Med. 2016 Oct 17;213(11):2503-2523. doi: 10.1084/jem.20160397. Epub 2016 Oct 10. J Exp Med. 2016. PMID: 27811057 Free PMC article.
tRNA Modification: Is Cancer Having a Wobble?
Rapino F, Delaunay S, Zhou Z, Chariot A, Close P. Rapino F, et al. Trends Cancer. 2017 Apr;3(4):249-252. doi: 10.1016/j.trecan.2017.02.004. Epub 2017 Mar 27. Trends Cancer. 2017. PMID: 28718436
Codon-specific translation reprogramming promotes resistance to targeted therapy.
Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, De Tullio P, Sin O, Shostak K, Schmitz S, Piepers J, Ghesquière B, Karim L, Charloteaux B, Jamart D, Florin A, Lambert C, Rorive A, Jerusalem G, Leucci E, Dewaele M, Vooijs M, Leidel SA, Georges M, Voz M, Peers B, Büttner R, Marine JC, Chariot A, Close P. Rapino F, et al. Nature. 2018 Jun;558(7711):605-609. doi: 10.1038/s41586-018-0243-7. Epub 2018 Jun 20. Nature. 2018. PMID: 29925953
29 results