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Molecular and epigenetic ex vivo profiling of testis cancer-associated fibroblasts and their interaction with germ cell tumor cells and macrophages.
Stephan A, Suhrmann JH, Skowron MA, Che Y, Poschmann G, Petzsch P, Kresbach C, Wruck W, Pongratanakul P, Adjaye J, Stühler K, Köhrer K, Schüller U, Nettersheim D. Stephan A, et al. Among authors: skowron ma. Matrix Biol. 2024 Sep;132:10-23. doi: 10.1016/j.matbio.2024.06.001. Epub 2024 Jun 6. Matrix Biol. 2024. PMID: 38851302 Free article.
ARID1A Regulates Transcription and the Epigenetic Landscape via POLE and DMAP1 while ARID1A Deficiency or Pharmacological Inhibition Sensitizes Germ Cell Tumor Cells to ATR Inhibition.
Kurz L, Miklyaeva A, Skowron MA, Overbeck N, Poschmann G, Becker T, Eul K, Kurz T, Schönberger S, Calaminus G, Stühler K, Dykhuizen E, Albers P, Nettersheim D. Kurz L, et al. Among authors: skowron ma. Cancers (Basel). 2020 Apr 7;12(4):905. doi: 10.3390/cancers12040905. Cancers (Basel). 2020. PMID: 32272809 Free PMC article.
CDK4/6 inhibition presents as a therapeutic option for paediatric and adult germ cell tumours and induces cell cycle arrest and apoptosis via canonical and non-canonical mechanisms.
Skowron MA, Vermeulen M, Winkelhausen A, Becker TK, Bremmer F, Petzsch P, Schönberger S, Calaminus G, Köhrer K, Albers P, Nettersheim D. Skowron MA, et al. Br J Cancer. 2020 Aug;123(3):378-391. doi: 10.1038/s41416-020-0891-x. Epub 2020 May 18. Br J Cancer. 2020. PMID: 32418994 Free PMC article.
Molecular and epigenetic pathogenesis of germ cell tumors.
Müller MR, Skowron MA, Albers P, Nettersheim D. Müller MR, et al. Among authors: skowron ma. Asian J Urol. 2021 Apr;8(2):144-154. doi: 10.1016/j.ajur.2020.05.009. Epub 2020 May 30. Asian J Urol. 2021. PMID: 33996469 Free PMC article. Review.
Profiling the 3D interaction between germ cell tumors and microenvironmental cells at the transcriptome and secretome level.
Skowron MA, Eul K, Stephan A, Ludwig GF, Wakileh GA, Bister A, Söhngen C, Raba K, Petzsch P, Poschmann G, Kuffour EO, Degrandi D, Ali S, Wiek C, Hanenberg H, Münk C, Stühler K, Köhrer K, Mass E, Nettersheim D. Skowron MA, et al. Mol Oncol. 2022 Sep;16(17):3107-3127. doi: 10.1002/1878-0261.13282. Epub 2022 Jul 26. Mol Oncol. 2022. PMID: 35811571 Free PMC article.
Establishment and Evaluation of Dual HDAC/BET Inhibitors as Therapeutic Options for Germ Cell Tumors and Other Urological Malignancies.
Burmeister A, Stephan A, Alves Avelar LA, Müller MR, Seiwert A, Höfmann S, Fischer F, Torres-Gomez H, Hoffmann MJ, Niegisch G, Bremmer F, Petzsch P, Köhrer K, Albers P, Kurz T, Skowron MA, Nettersheim D. Burmeister A, et al. Among authors: skowron ma. Mol Cancer Ther. 2022 Nov 3;21(11):1674-1688. doi: 10.1158/1535-7163.MCT-22-0207. Mol Cancer Ther. 2022. PMID: 35999659 Free PMC article.
Characterizing the mutational burden, DNA methylation landscape, and proteome of germ cell tumor-related somatic-type malignancies to identify the tissue-of-origin, mechanisms of therapy resistance, and druggable targets.
Bremmer F, Pongratanakul P, Skowron M, Che Y, Richter A, Küffer S, Reuter-Jessen K, Bohnenberger H, Pauls S, Kresbach C, Schüller U, Stühler K, Ströbel P, Albers P, Nettersheim D. Bremmer F, et al. Br J Cancer. 2023 Nov;129(10):1580-1589. doi: 10.1038/s41416-023-02425-5. Epub 2023 Sep 19. Br J Cancer. 2023. PMID: 37726478 Free PMC article.
Assessing the risk to develop a growing teratoma syndrome based on molecular and epigenetic subtyping as well as novel secreted biomarkers.
Pongratanakul P, Bremmer F, Pauls S, Poschmann G, Kresbach C, Parmaksiz F, Skowron MA, Fuß J, Stephan A, Paffenholz P, Stühler K, Schüller U, Ströbel P, Heidenreich A, Che Y, Albers P, Nettersheim D. Pongratanakul P, et al. Among authors: skowron ma. Cancer Lett. 2024 Mar 31;585:216673. doi: 10.1016/j.canlet.2024.216673. Epub 2024 Jan 29. Cancer Lett. 2024. PMID: 38296184 Free article.
37 results