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Page 1
Engineering an inducible leukemia-associated fusion protein enables large-scale ex vivo production of functional human phagocytes.
Windisch R, Soliman S, Hoffmann A, Chen-Wichmann L, Danese A, Vosberg S, Bravo J, Lutz S, Kellner C, Fischer A, Gebhard C, Redondo Monte E, Hartmann L, Schneider S, Beier F, Strobl CD, Weigert O, Peipp M, Schündeln M, Stricker SH, Rehli M, Bernhagen J, Humpe A, Klump H, Brendel C, Krause DS, Greif PA, Wichmann C. Windisch R, et al. Among authors: vosberg s. Proc Natl Acad Sci U S A. 2024 Jun 18;121(25):e2312499121. doi: 10.1073/pnas.2312499121. Epub 2024 Jun 10. Proc Natl Acad Sci U S A. 2024. PMID: 38857395 Free PMC article.
ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.
Hartmann L, Dutta S, Opatz S, Vosberg S, Reiter K, Leubolt G, Metzeler KH, Herold T, Bamopoulos SA, Bräundl K, Zellmeier E, Ksienzyk B, Konstandin NP, Schneider S, Hopfner KP, Graf A, Krebs S, Blum H, Middeke JM, Stölzel F, Thiede C, Wolf S, Bohlander SK, Preiss C, Chen-Wichmann L, Wichmann C, Sauerland MC, Büchner T, Berdel WE, Wörmann BJ, Braess J, Hiddemann W, Spiekermann K, Greif PA. Hartmann L, et al. Among authors: vosberg s. Nat Commun. 2016 Jun 2;7:11733. doi: 10.1038/ncomms11733. Nat Commun. 2016. PMID: 27252013 Free PMC article.
Close correlation of copy number aberrations detected by next-generation sequencing with results from routine cytogenetics in acute myeloid leukemia.
Vosberg S, Herold T, Hartmann L, Neumann M, Opatz S, Metzeler KH, Schneider S, Graf A, Krebs S, Blum H, Baldus CD, Hiddemann W, Spiekermann K, Bohlander SK, Mansmann U, Greif PA. Vosberg S, et al. Genes Chromosomes Cancer. 2016 Jul;55(7):553-67. doi: 10.1002/gcc.22359. Epub 2016 May 2. Genes Chromosomes Cancer. 2016. PMID: 27015608
The clinical mutatome of core binding factor leukemia.
Opatz S, Bamopoulos SA, Metzeler KH, Herold T, Ksienzyk B, Bräundl K, Tschuri S, Vosberg S, Konstandin NP, Wang C, Hartmann L, Graf A, Krebs S, Blum H, Schneider S, Thiede C, Middeke JM, Stölzel F, Röllig C, Schetelig J, Ehninger G, Krämer A, Braess J, Görlich D, Sauerland MC, Berdel WE, Wörmann BJ, Hiddemann W, Spiekermann K, Bohlander SK, Greif PA. Opatz S, et al. Among authors: vosberg s. Leukemia. 2020 Jun;34(6):1553-1562. doi: 10.1038/s41375-019-0697-0. Epub 2020 Jan 2. Leukemia. 2020. PMID: 31896782 Free PMC article.
DNA methylation epitypes highlight underlying developmental and disease pathways in acute myeloid leukemia.
Giacopelli B, Wang M, Cleary A, Wu YZ, Schultz AR, Schmutz M, Blachly JS, Eisfeld AK, Mundy-Bosse B, Vosberg S, Greif PA, Claus R, Bullinger L, Garzon R, Coombes KR, Bloomfield CD, Druker BJ, Tyner JW, Byrd JC, Oakes CC. Giacopelli B, et al. Among authors: vosberg s. Genome Res. 2021 May;31(5):747-761. doi: 10.1101/gr.269233.120. Epub 2021 Mar 11. Genome Res. 2021. PMID: 33707228 Free PMC article.
Relapse of acute myeloid leukemia after allogeneic stem cell transplantation is associated with gain of WT1 alterations and high mutation load.
Vosberg S, Hartmann L, Metzeler KH, Konstandin NP, Schneider S, Varadharajan A, Hauser A, Krebs S, Blum H, Bohlander SK, Hiddemann W, Tischer J, Spiekermann K, Greif PA. Vosberg S, et al. Haematologica. 2018 Dec;103(12):e581-e584. doi: 10.3324/haematol.2018.193102. Epub 2018 Jun 28. Haematologica. 2018. PMID: 29954937 Free PMC article. No abstract available.
Exome sequencing identifies recurring FLT3 N676K mutations in core-binding factor leukemia.
Opatz S, Polzer H, Herold T, Konstandin NP, Ksienzyk B, Zellmeier E, Vosberg S, Graf A, Krebs S, Blum H, Hopfner KP, Kakadia PM, Schneider S, Dufour A, Braess J, Sauerland MC, Berdel WE, Büchner T, Woermann BJ, Hiddemann W, Spiekermann K, Bohlander SK, Greif PA. Opatz S, et al. Among authors: vosberg s. Blood. 2013 Sep 5;122(10):1761-9. doi: 10.1182/blood-2013-01-476473. Epub 2013 Jul 22. Blood. 2013. PMID: 23878140 Free article. Clinical Trial.
The target cell of transformation is distinct from the leukemia stem cell in murine CALM/AF10 leukemia models.
Dutta S, Krause A, Vosberg S, Herold T, Ksienzyk B, Quintanilla-Martinez L, Tizazu B, Chopra M, Graf A, Krebs S, Blum H, Greif PA, Vetter A, Metzeler K, Rothenberg-Thurley M, Schneider MR, Dahlhoff M, Spiekermann K, Zimber-Strobl U, Wolf E, Bohlander SK. Dutta S, et al. Among authors: vosberg s. Leukemia. 2016 May;30(5):1166-76. doi: 10.1038/leu.2015.349. Epub 2015 Dec 21. Leukemia. 2016. PMID: 26686248
32 results