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Discovery, Multiparametric Optimization, and Solid-State Driven Identification of CHF-6550, a Novel Soft Dual Pharmacology Muscarinic Antagonist and β2 Agonist (MABA) for the Inhaled Treatment of Respiratory Diseases.
Carzaniga L, Linney ID, Rizzi A, Schmidt W, Knight CK, Mileo V, Amadei F, Pastore F, Miglietta D, Cesari N, Riccardi B, Mazzucato R, Ghidini E, Blackaby WP, Patacchini R, Battipaglia L, Villetti G, Puccini P, Catinella S, Civelli M, Rancati F. Carzaniga L, et al. Among authors: rizzi a. J Med Chem. 2024 Jun 27;67(12):9816-9841. doi: 10.1021/acs.jmedchem.4c00298. Epub 2024 Jun 10. J Med Chem. 2024. PMID: 38857426
Optimization of M3 Antagonist-PDE4 Inhibitor (MAPI) Dual Pharmacology Molecules for the Treatment of COPD.
Rizzi A, Amari G, Pivetti F, Delcanale M, Amadei F, Pappani A, Fornasari L, Villetti G, Marchini G, Pisano AR, Pitozzi V, Pittelli MG, Trevisani M, Salvadori M, Cenacchi V, Fioni A, Puccini P, Civelli M, Patacchini R, Baker-Glenn C, Van de Poël H, Blackaby W, Nash K, Armani E. Rizzi A, et al. J Med Chem. 2023 Aug 24;66(16):11476-11497. doi: 10.1021/acs.jmedchem.3c01012. Epub 2023 Aug 10. J Med Chem. 2023. PMID: 37561958
Discovery of a Potent, Selective, and Orally Bioavailable Tool Compound for Probing the Role of Lysophosphatidic Acid Type 2 Receptor Antagonists in Fibrotic Disorders.
Armani E, Rizzi A, Iotti N, Saccani F, Di Lascia MR, Tigli L, Pappani A, Marchini G, Murgo A, Capelli AM, Delcanale M, Puccini P, Villetti G, Civelli M, Beato C, Giuliani M, Mundi C, Murarolli F, Pagano M, Raveglia LF, Remelli R, Amari G. Armani E, et al. Among authors: rizzi a. J Med Chem. 2023 Apr 27;66(8):5622-5656. doi: 10.1021/acs.jmedchem.2c02087. Epub 2023 Apr 5. J Med Chem. 2023. PMID: 37017110
Stability of the thromboxane B2 biomarker of low-dose aspirin pharmacodynamics in human whole blood and in long-term stored serum samples.
Petrucci G, Rizzi A, Bellavia S, Dentali F, Frisullo G, Pitocco D, Ranalli P, Rizzo PA, Scala I, Silingardi M, Zagarrì E, Gussoni G, Rocca B. Petrucci G, et al. Among authors: rizzi a. Res Pract Thromb Haemost. 2024 Nov 12;8(8):102623. doi: 10.1016/j.rpth.2024.102623. eCollection 2024 Nov. Res Pract Thromb Haemost. 2024. PMID: 39698184 Free PMC article.
Searches for Pair-Produced Multijet Resonances Using Data Scouting in Proton-Proton Collisions at sqrt[s]=13  TeV.
Hayrapetyan A, Tumasyan A, Adam W, Andrejkovic JW, Bergauer T, Chatterjee S, Damanakis K, Dragicevic M, Hussain PS, Jeitler M, Krammer N, Li A, Liko D, Mikulec I, Schieck J, Schöfbeck R, Schwarz D, Sonawane M, Templ S, Waltenberger W, Wulz CE, Darwish MR, Janssen T, Van Mechelen P, Breugelmans N, D'Hondt J, Dansana S, De Moor A, Delcourt M, Heyen F, Lowette S, Makarenko I, Müller D, Tavernier S, Tytgat M, Van Onsem GP, Van Putte S, Vannerom D, Clerbaux B, Das AK, De Lentdecker G, Evard H, Favart L, Gianneios P, Hohov D, Jaramillo J, Khalilzadeh A, Khan FA, Lee K, Mahdavikhorrami M, Malara A, Paredes S, Thomas L, Vanden Bemden M, Vander Velde C, Vanlaer P, De Coen M, Dobur D, Gokbulut G, Hong Y, Knolle J, Lambrecht L, Marckx D, Mestdach G, Mota Amarilo K, Rendón C, Samalan A, Skovpen K, Van Den Bossche N, van der Linden J, Wezenbeek L, Benecke A, Bethani A, Bruno G, Caputo C, De Favereau De Jeneret J, Delaere C, Donertas IS, Giammanco A, Guzel AO, Jain S, Lemaitre V, Lidrych J, Mastrapasqua P, Tran TT, Wertz S, Alves GA, Coelho E, Hensel C, Menezes De Oliveira T, Moraes A, Rebello Teles P, Soeiro M, Vilela Pereira A, Aldá Júnior WL, Alves Gallo Pereira M, Barroso Ferreira Filho M, … See abstract for full author list ➔ Hayrapetyan A, et al. Among authors: rizzi a. Phys Rev Lett. 2024 Nov 15;133(20):201803. doi: 10.1103/PhysRevLett.133.201803. Phys Rev Lett. 2024. PMID: 39626745
992 results