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Discovery, Multiparametric Optimization, and Solid-State Driven Identification of CHF-6550, a Novel Soft Dual Pharmacology Muscarinic Antagonist and β2 Agonist (MABA) for the Inhaled Treatment of Respiratory Diseases.
Carzaniga L, Linney ID, Rizzi A, Schmidt W, Knight CK, Mileo V, Amadei F, Pastore F, Miglietta D, Cesari N, Riccardi B, Mazzucato R, Ghidini E, Blackaby WP, Patacchini R, Battipaglia L, Villetti G, Puccini P, Catinella S, Civelli M, Rancati F. Carzaniga L, et al. Among authors: villetti g. J Med Chem. 2024 Jun 27;67(12):9816-9841. doi: 10.1021/acs.jmedchem.4c00298. Epub 2024 Jun 10. J Med Chem. 2024. PMID: 38857426
Mechanisms of action of CHF3381 in the forebrain.
Barbieri M, Bregola G, Buzzi A, Marino S, Zucchini S, Stables JP, Bergamaschi M, Pietra C, Villetti G, Simonato M. Barbieri M, et al. Among authors: villetti g. Br J Pharmacol. 2003 Aug;139(7):1333-41. doi: 10.1038/sj.bjp.0705381. Br J Pharmacol. 2003. PMID: 12890713 Free PMC article.
Synthesis and biological activity of flurbiprofen analogues as selective inhibitors of beta-amyloid(1)(-)(42) secretion.
Peretto I, Radaelli S, Parini C, Zandi M, Raveglia LF, Dondio G, Fontanella L, Misiano P, Bigogno C, Rizzi A, Riccardi B, Biscaioli M, Marchetti S, Puccini P, Catinella S, Rondelli I, Cenacchi V, Bolzoni PT, Caruso P, Villetti G, Facchinetti F, Del Giudice E, Moretto N, Imbimbo BP. Peretto I, et al. Among authors: villetti g. J Med Chem. 2005 Sep 8;48(18):5705-20. doi: 10.1021/jm0502541. J Med Chem. 2005. PMID: 16134939
99 results