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621 results

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Chronic treatment with glucagon-like peptide-1 and glucagon receptor co-agonist causes weight loss-independent improvements in hepatic steatosis in mice with diet-induced obesity.
McGlone ER, Hope DCD, Davies I, Dore M, Goldin R, Jones B, Liu Z, Li JV, Vorkas PA, Khoo B, Carling D, Minnion J, Bloom SR, Tan TM. McGlone ER, et al. Among authors: davies i. Biomed Pharmacother. 2024 Jul;176:116888. doi: 10.1016/j.biopha.2024.116888. Epub 2024 Jun 10. Biomed Pharmacother. 2024. PMID: 38861859 Free article.
Hypoaminoacidemia underpins glucagon-mediated energy expenditure and weight loss.
Hope DCD, Hinds CE, Lopes T, Vincent ML, Shrewsbury JV, Yu ATC, Davies I, Scott R, Jones B, Murphy KG, Minnion JS, Sardini A, Carling D, Lutz TA, Bloom SR, Tan TMM, Owen BM. Hope DCD, et al. Among authors: davies i. Cell Rep Med. 2022 Nov 15;3(11):100810. doi: 10.1016/j.xcrm.2022.100810. Cell Rep Med. 2022. PMID: 36384093 Free PMC article.
Adaptive infusion of a glucagon-like peptide-1/glucagon receptor co-agonist G3215, in adults with overweight or obesity: Results from a phase 1 randomized clinical trial.
Hope DCD, Ansari S, Choudhury S, Alexiadou K, Tabbakh Y, Ilesanmi I, Lazarus K, Davies I, Jimenez-Pacheco L, Yang W, Ball LJ, Malviya R, Reglinska B, Khoo B, Minnion J, Bloom SR, Tan TM. Hope DCD, et al. Among authors: davies i. Diabetes Obes Metab. 2024 Apr;26(4):1479-1491. doi: 10.1111/dom.15448. Epub 2024 Jan 16. Diabetes Obes Metab. 2024. PMID: 38229453 Clinical Trial.
PCSK9 in metabolism and diseases.
Ajoolabady A, Pratico D, Mazidi M, Davies IG, Lip GYH, Seidah N, Libby P, Kroemer G, Ren J. Ajoolabady A, et al. Among authors: davies ig. Metabolism. 2024 Nov 14;163:156064. doi: 10.1016/j.metabol.2024.156064. Online ahead of print. Metabolism. 2024. PMID: 39547595 Review.
621 results