Palle K - Search Results

1

CHK1 inhibitor induced PARylation by targeting PARG causes excessive replication and metabolic stress and overcomes chemoresistance in ovarian cancer.

Acharya G, Mani C, Sah N, Saamarthy K, Young R, Reedy MB, Sobol RW, Palle K. Acharya G, et al. Among authors: palle k. Cell Death Discov. 2024 Jun 11;10(1):278. doi: 10.1038/s41420-024-02040-0. Cell Death Discov. 2024. PMID: 38862485 Free PMC article.

2

Hedgehog/GLI1 Transcriptionally Regulates FANCD2 in Ovarian Tumor Cells: Its Inhibition Induces HR-Deficiency and Synergistic Lethality with PARP Inhibition.

Mani C, Tripathi K, Chaudhary S, Somasagara RR, Rocconi RP, Crasto C, Reedy M, Athar M, Palle K. Mani C, et al. Among authors: palle k. Neoplasia. 2021 Sep;23(9):1002-1015. doi: 10.1016/j.neo.2021.06.010. Epub 2021 Aug 8. Neoplasia. 2021. PMID: 34380074 Free PMC article.

3

GLI1-targeting drugs induce replication stress and homologous recombination deficiency and synergize with PARP-targeted therapies in triple negative breast cancer cells.

Mani C, Tripathi K, Omy TR, Reedy M, Manne U, Palle K. Mani C, et al. Among authors: palle k. Biochim Biophys Acta Mol Basis Dis. 2022 Feb 1;1868(2):166300. doi: 10.1016/j.bbadis.2021.166300. Epub 2021 Nov 6. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 34748904 Free article.

4

Racial differences in RAD51 expression are regulated by miRNA-214-5P and its inhibition synergizes with olaparib in triple-negative breast cancer.

Mani C, Acharya G, Saamarthy K, Ochola D, Mereddy S, Pruitt K, Manne U, Palle K. Mani C, et al. Among authors: palle k. Breast Cancer Res. 2023 Apr 20;25(1):44. doi: 10.1186/s13058-023-01615-6. Breast Cancer Res. 2023. PMID: 37081516 Free PMC article.

5

RAD6 promotes chemoresistance in ovarian cancer.

Clark DW, Mani C, Palle K. Clark DW, et al. Among authors: palle k. Mol Cell Oncol. 2017 Dec 18;5(1):e1392403. doi: 10.1080/23723556.2017.1392403. eCollection 2018. Mol Cell Oncol. 2017. PMID: 29404391 Free PMC article.

6

Thymineless Death by the Fluoropyrimidine Polymer F10 Involves Replication Fork Collapse and Is Enhanced by Chk1 Inhibition.

Mani C, Pai S, Papke CM, Palle K, Gmeiner WH. Mani C, et al. Among authors: palle k. Neoplasia. 2018 Dec;20(12):1236-1245. doi: 10.1016/j.neo.2018.10.006. Epub 2018 Nov 12. Neoplasia. 2018. PMID: 30439567 Free PMC article.

7

DNA repair fidelity in stem cell maintenance, health, and disease.

Mani C, Reddy PH, Palle K. Mani C, et al. Among authors: palle k. Biochim Biophys Acta Mol Basis Dis. 2020 Apr 1;1866(4):165444. doi: 10.1016/j.bbadis.2019.03.017. Epub 2019 Apr 4. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 30953688 Free PMC article. Review.

8

A Novel Role for BRIP1/FANCJ in Neuronal Cells Health and in Resolving Oxidative Stress-Induced DNA Lesions.

Mani C, Acharya G, Kshirsagar S, Vijayan M, Khan H, Reddy PH, Palle K. Mani C, et al. Among authors: palle k. J Alzheimers Dis. 2022;85(1):207-221. doi: 10.3233/JAD-215305. J Alzheimers Dis. 2022. PMID: 34776453

9

Case Report: Intra-Tumoral Vaccinations of Quadrivalent HPV-L1 Peptide Vaccine With Topical TLR-7 Agonist Following Recurrence: Complete Resolution of HPV-HR-Associated Gynecologic Squamous Cell Carcinomas in Two Patients.

Reedy M, Jonnalagadda S, Palle K. Reedy M, et al. Among authors: palle k. Pathol Oncol Res. 2021 Dec 20;27:1609922. doi: 10.3389/pore.2021.1609922. eCollection 2021. Pathol Oncol Res. 2021. PMID: 34987310 Free PMC article.

10

Prexasertib treatment induces homologous recombination deficiency and synergizes with olaparib in triple-negative breast cancer cells.

Mani C, Jonnalagadda S, Lingareddy J, Awasthi S, Gmeiner WH, Palle K. Mani C, et al. Among authors: palle k. Breast Cancer Res. 2019 Sep 6;21(1):104. doi: 10.1186/s13058-019-1192-2. Breast Cancer Res. 2019. PMID: 31492187 Free PMC article.

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