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Page 1
Pigment epithelium derived factor drives melanocyte proliferation and migration in neurofibromatosis café au lait macules.
Lovatt C, Williams M, Gibbs A, Mukhtar A, Morgan HJ, Lanfredini S, Olivero C, Spurlock G, Davies S, Philpott C, Tovell H, Turnpenny P, Baban D, Knight S, Brems H, Sampson JR, Legius E, Upadhyaya M, Patel GK. Lovatt C, et al. Skin Health Dis. 2024 Jun 24;4(5):e394. doi: 10.1002/ski2.394. eCollection 2024 Oct. Skin Health Dis. 2024. PMID: 39355740 Free PMC article.
Structure- and Property-Based Optimization of Efficient Pan-Bromodomain and Extra Terminal Inhibitors to Identify Oral and Intravenous Candidate I-BET787.
Hirst DJ, Bamborough P, Al-Mahdi N, Angell DC, Barnett HA, Baxter A, Bit RA, Brown JA, Chung CW, Craggs PD, Davis RP, Demont EH, Ferrie A, Gordon LJ, Harada I, Ho TCT, Holyer ID, Hooper-Greenhill E, Jones KL, Lindon MJ, Lovatt C, Lugo D, Maller C, McGonagle G, Messenger C, Mitchell DJ, Pascoe DD, Patel VK, Patten C, Poole DL, Shah RR, Rioja I, Stafford KAJ, Tape D, Taylor S, Theodoulou NH, Tomlinson L, Wall ID, Wellaway CR, White G, Prinjha RK, Humphreys PG. Hirst DJ, et al. Among authors: lovatt c. J Med Chem. 2024 Jun 27;67(12):10464-10489. doi: 10.1021/acs.jmedchem.4c00959. Epub 2024 Jun 12. J Med Chem. 2024. PMID: 38866424
Engineering Adenoviral Vectors with Improved GBM Selectivity.
Bates EA, Lovatt C, Plein AR, Davies JA, Siebzehnrubl FA, Parker AL. Bates EA, et al. Among authors: lovatt c. Viruses. 2023 Apr 28;15(5):1086. doi: 10.3390/v15051086. Viruses. 2023. PMID: 37243172 Free PMC article.
Design, Synthesis, and Characterization of I-BET567, a Pan-Bromodomain and Extra Terminal (BET) Bromodomain Oral Candidate.
Humphreys PG, Atkinson SJ, Bamborough P, Bit RA, Chung CW, Craggs PD, Cutler L, Davis R, Ferrie A, Gong G, Gordon LJ, Gray M, Harrison LA, Hayhow TG, Haynes A, Henley N, Hirst DJ, Holyer ID, Lindon MJ, Lovatt C, Lugo D, McCleary S, Molnar J, Osmani Q, Patten C, Preston A, Rioja I, Seal JT, Smithers N, Sun F, Tang D, Taylor S, Theodoulou NH, Thomas C, Watson RJ, Wellaway CR, Zhu L, Tomkinson NCO, Prinjha RK. Humphreys PG, et al. Among authors: lovatt c. J Med Chem. 2022 Feb 10;65(3):2262-2287. doi: 10.1021/acs.jmedchem.1c01747. Epub 2022 Jan 7. J Med Chem. 2022. PMID: 34995458 Free article.
41 results