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C16ORF70/MYTHO promotes healthy aging in C.elegans and prevents cellular senescence in mammals.
Franco-Romero A, Morbidoni V, Milan G, Sartori R, Wulff J, Romanello V, Armani A, Salviati L, Conte M, Salvioli S, Franceschi C, Buonomo V, Swoboda CO, Grumati P, Pannone L, Martinelli S, Jefferies HB, Dikic I, van der Laan J, Cabreiro F, Millay DP, Tooze SA, Trevisson E, Sandri M. Franco-Romero A, et al. Among authors: cabreiro f. J Clin Invest. 2024 Jun 13;134(15):e165814. doi: 10.1172/JCI165814. J Clin Invest. 2024. PMID: 38869949 Free PMC article.
Microbes put drugs in(action).
van der Laan J, Cabreiro F. van der Laan J, et al. Among authors: cabreiro f. Trends Endocrinol Metab. 2025 Jan;36(1):7-10. doi: 10.1016/j.tem.2024.08.005. Epub 2024 Sep 3. Trends Endocrinol Metab. 2025. PMID: 39232910 Free article. Review.
Increased fidelity of protein synthesis extends lifespan.
Martinez-Miguel VE, Lujan C, Espie-Caullet T, Martinez-Martinez D, Moore S, Backes C, Gonzalez S, Galimov ER, Brown AEX, Halic M, Tomita K, Rallis C, von der Haar T, Cabreiro F, Bjedov I. Martinez-Miguel VE, et al. Among authors: cabreiro f. Cell Metab. 2021 Nov 2;33(11):2288-2300.e12. doi: 10.1016/j.cmet.2021.08.017. Epub 2021 Sep 14. Cell Metab. 2021. PMID: 34525330 Free PMC article.
Bioaccumulation of therapeutic drugs by human gut bacteria.
Klünemann M, Andrejev S, Blasche S, Mateus A, Phapale P, Devendran S, Vappiani J, Simon B, Scott TA, Kafkia E, Konstantinidis D, Zirngibl K, Mastrorilli E, Banzhaf M, Mackmull MT, Hövelmann F, Nesme L, Brochado AR, Maier L, Bock T, Periwal V, Kumar M, Kim Y, Tramontano M, Schultz C, Beck M, Hennig J, Zimmermann M, Sévin DC, Cabreiro F, Savitski MM, Bork P, Typas A, Patil KR. Klünemann M, et al. Among authors: cabreiro f. Nature. 2021 Sep;597(7877):533-538. doi: 10.1038/s41586-021-03891-8. Epub 2021 Sep 8. Nature. 2021. PMID: 34497420 Free PMC article.
C. elegans: A biosensor for host-microbe interactions.
Backes C, Martinez-Martinez D, Cabreiro F. Backes C, et al. Among authors: cabreiro f. Lab Anim (NY). 2021 May;50(5):127-135. doi: 10.1038/s41684-021-00724-z. Epub 2021 Mar 1. Lab Anim (NY). 2021. PMID: 33649581 Review.
ARDD 2020: from aging mechanisms to interventions.
Mkrtchyan GV, Abdelmohsen K, Andreux P, Bagdonaite I, Barzilai N, Brunak S, Cabreiro F, de Cabo R, Campisi J, Cuervo AM, Demaria M, Ewald CY, Fang EF, Faragher R, Ferrucci L, Freund A, Silva-García CG, Georgievskaya A, Gladyshev VN, Glass DJ, Gorbunova V, de Grey A, He WW, Hoeijmakers J, Hoffmann E, Horvath S, Houtkooper RH, Jensen MK, Jensen MB, Kane A, Kassem M, de Keizer P, Kennedy B, Karsenty G, Lamming DW, Lee KF, MacAulay N, Mamoshina P, Mellon J, Molenaars M, Moskalev A, Mund A, Niedernhofer L, Osborne B, Pak HH, Parkhitko A, Raimundo N, Rando TA, Rasmussen LJ, Reis C, Riedel CG, Franco-Romero A, Schumacher B, Sinclair DA, Suh Y, Taub PR, Toiber D, Treebak JT, Valenzano DR, Verdin E, Vijg J, Young S, Zhang L, Bakula D, Zhavoronkov A, Scheibye-Knudsen M. Mkrtchyan GV, et al. Among authors: cabreiro f. Aging (Albany NY). 2020 Dec 30;12(24):24484-24503. doi: 10.18632/aging.202454. Epub 2020 Dec 30. Aging (Albany NY). 2020. PMID: 33378272 Free PMC article. Review.
Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila.
Bjedov I, Cochemé HM, Foley A, Wieser D, Woodling NS, Castillo-Quan JI, Norvaisas P, Lujan C, Regan JC, Toivonen JM, Murphy MP, Thornton J, Kinghorn KJ, Neufeld TP, Cabreiro F, Partridge L. Bjedov I, et al. Among authors: cabreiro f. PLoS Genet. 2020 Nov 30;16(11):e1009083. doi: 10.1371/journal.pgen.1009083. eCollection 2020 Nov. PLoS Genet. 2020. PMID: 33253201 Free PMC article.
35 results