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Page 1
High-Efficiency, Selection-free Gene Repair in Airway Stem Cells from Cystic Fibrosis Patients Rescues CFTR Function in Differentiated Epithelia.
Vaidyanathan S, Salahudeen AA, Sellers ZM, Bravo DT, Choi SS, Batish A, Le W, Baik R, de la O S, Kaushik MP, Galper N, Lee CM, Teran CA, Yoo JH, Bao G, Chang EH, Patel ZM, Hwang PH, Wine JJ, Milla CE, Desai TJ, Nayak JV, Kuo CJ, Porteus MH. Vaidyanathan S, et al. Among authors: sellers zm. Cell Stem Cell. 2020 Feb 6;26(2):161-171.e4. doi: 10.1016/j.stem.2019.11.002. Epub 2019 Dec 12. Cell Stem Cell. 2020. PMID: 31839569 Free PMC article.
Targeted replacement of full-length CFTR in human airway stem cells by CRISPR-Cas9 for pan-mutation correction in the endogenous locus.
Vaidyanathan S, Baik R, Chen L, Bravo DT, Suarez CJ, Abazari SM, Salahudeen AA, Dudek AM, Teran CA, Davis TH, Lee CM, Bao G, Randell SH, Artandi SE, Wine JJ, Kuo CJ, Desai TJ, Nayak JV, Sellers ZM, Porteus MH. Vaidyanathan S, et al. Among authors: sellers zm. Mol Ther. 2022 Jan 5;30(1):223-237. doi: 10.1016/j.ymthe.2021.03.023. Epub 2021 Mar 29. Mol Ther. 2022. PMID: 33794364 Free PMC article.
Impaired distal colonic pH in adults with cystic fibrosis.
Patel D, Mathews S, van Unen V, Chan JE, Al-Hammadi N, Borowitz D, Gelfond D, Sellers ZM. Patel D, et al. Among authors: sellers zm. J Cyst Fibros. 2023 Mar;22(2):290-295. doi: 10.1016/j.jcf.2022.12.011. Epub 2022 Dec 24. J Cyst Fibros. 2023. PMID: 36572613 Free PMC article.
Key role of down-regulated in adenoma (SLC26A3) chloride/bicarbonate exchanger in linaclotide-stimulated intestinal bicarbonate secretion upon loss of CFTR function.
Sarthi JB, Trumbull AM, Abazari SM, van Unen V, Chan JE, Jiang Y, Gammons J, Anderson MO, Cil O, Kuo CJ, Sellers ZM. Sarthi JB, et al. Among authors: sellers zm. bioRxiv [Preprint]. 2024 Apr 22:2023.05.05.539132. doi: 10.1101/2023.05.05.539132. bioRxiv. 2024. PMID: 37205513 Free PMC article. Preprint.
A human autoimmune organoid model reveals IL-7 function in coeliac disease.
Santos AJM, van Unen V, Lin Z, Chirieleison SM, Ha N, Batish A, Chan JE, Cedano J, Zhang ET, Mu Q, Guh-Siesel A, Tomaske M, Colburg D, Varma S, Choi SS, Christophersen A, Baghdasaryan A, Yost KE, Karlsson K, Ha A, Li J, Dai H, Sellers ZM, Chang HY, Dunn JCY, Zhang BM, Mellins ED, Sollid LM, Fernandez-Becker NQ, Davis MM, Kuo CJ. Santos AJM, et al. Among authors: sellers zm. Nature. 2024 Aug;632(8024):401-410. doi: 10.1038/s41586-024-07716-2. Epub 2024 Jul 24. Nature. 2024. PMID: 39048815
A role for guanylate cyclase C in acid-stimulated duodenal mucosal bicarbonate secretion.
Rao SP, Sellers Z, Crombie DL, Hogan DL, Mann EA, Childs D, Keely S, Sheil-Puopolo M, Giannella RA, Barrett KE, Isenberg JI, Pratha VS. Rao SP, et al. Am J Physiol Gastrointest Liver Physiol. 2004 Jan;286(1):G95-G101. doi: 10.1152/ajpgi.00087.2003. Epub 2003 Jul 24. Am J Physiol Gastrointest Liver Physiol. 2004. PMID: 12881226 Free article.
61 results