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388 results

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Page 1
Activation of NOTCH signaling impedes cell proliferation and survival in acute megakaryoblastic leukemia.
Ong KOK, Mok MMH, Niibori-Nambu A, Du L, Yanagida M, Wang CQ, Bahirvani AG, Chin DWL, Koh CP, Ng KP, Yamashita N, Jacob B, Yokomizo T, Takizawa H, Matsumura T, Suda T, Lau JA, Tan TZ, Mori S, Yang H, Iwasaki M, Minami T, Asou N, Sun QY, Ding LW, Koeffler HP, Tenen DG, Shimizu R, Yamamoto M, Ito Y, Kham SKY, Yeoh AE, Chng WJ, Osato M. Ong KOK, et al. Among authors: chng wj. Exp Hematol. 2024 Sep;137:104255. doi: 10.1016/j.exphem.2024.104255. Epub 2024 Jun 13. Exp Hematol. 2024. PMID: 38876252
Integrin-α9 overexpression underlies the niche-independent maintenance of leukemia stem cells in acute myeloid leukemia.
Niibori-Nambu A, Wang CQ, Chin DWL, Chooi JY, Hosoi H, Sonoki T, Tham CY, Nah GSS, Cirovic B, Tan DQ, Takizawa H, Sashida G, Goh Y, Tng J, Fam WN, Fullwood MJ, Suda T, Yang H, Tergaonkar V, Taniuchi I, Li S, Chng WJ, Osato M. Niibori-Nambu A, et al. Among authors: chng wj. Gene. 2024 Nov 30;928:148761. doi: 10.1016/j.gene.2024.148761. Epub 2024 Jul 11. Gene. 2024. PMID: 39002785
Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growth.
Zhang Y, Chen K, Tang SC, Cai Y, Nambu A, See YX, Fu C, Raju A, Lebeau B, Ling Z, Chan JJ, Tay Y, Mutwil M, Lakshmanan M, Tucker-Kellogg G, Chng WJ, Tenen DG, Osato M, Tergaonkar V, Fullwood MJ. Zhang Y, et al. Among authors: chng wj. Nat Struct Mol Biol. 2024 Sep 20. doi: 10.1038/s41594-024-01391-7. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 39304765
Targeting the ubiquitin pathway in lymphoid malignancies.
Li B, Adam Eichhorn PJ, Chng WJ. Li B, et al. Among authors: chng wj. Cancer Lett. 2024 Jul 10;594:216978. doi: 10.1016/j.canlet.2024.216978. Epub 2024 May 24. Cancer Lett. 2024. PMID: 38795760 Free article. Review.
Acute Promyelocytic Leukemia Asian Consortium study of arsenic trioxide in newly-diagnosed patients: impact and outcome.
Gill H, Raghupathy R, Hou HA, Tsai XC, Tantiworawit A, Ooi MG, Gan GG, Wong CL, Yim RLH, Chin L, Lee P, Li VWK, Au L, Zhang Q, Leung GMK, Wu TKY, Lee YYC, Chng WJ, Tien HF, Kumana CR, Kwong YL. Gill H, et al. Among authors: chng wj. Blood Adv. 2024 Dec 18:bloodadvances.2024014999. doi: 10.1182/bloodadvances.2024014999. Online ahead of print. Blood Adv. 2024. PMID: 39693517
Presence of 1q21 Gain and Amplification May be Associated With Poorer Outcomes in Daratumumab-treated Multiple Myeloma Patients.
Lim KJC, Wellard C, Moore E, Ninkovic S, Chng WJ, Spencer A, Mollee P, Hocking J, Ho PJ, Janowski W, Kim K, McCaughan G, Dun K, McQuilten ZK, Chen F, Quach H. Lim KJC, et al. Among authors: chng wj. Clin Lymphoma Myeloma Leuk. 2024 Nov 9:S2152-2650(24)02402-9. doi: 10.1016/j.clml.2024.11.002. Online ahead of print. Clin Lymphoma Myeloma Leuk. 2024. PMID: 39616008 No abstract available.
388 results