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Patients taking benralizumab, dupilumab, or mepolizumab have lower postvaccination SARS-CoV-2 immunity.
Runnstrom MC, Lamothe PA, Faliti CE, Cheedarla N, Moreno A, Suthar MS, Nahata R, Ravindran M, Haddad NS, Morrison-Porter A, Quehl H, Ramonell RP, Woodruff M, Anam F, Zhang R, Swenson C, Polito C, Neveu W, Patel R, Smirnova N, Nguyen DC, Kim C, Hentenaar I, Kyu S, Usman S, Ngo T, Guo Z, Wu H, Daiss JL, Park J, Manning KE, Wali B, Ellis ML, Sharma S, Holguin F, Cheedarla S, Neish AS, Roback JD, Sanz I, Eun-Hyung Lee F. Runnstrom MC, et al. Among authors: sanz i. J Allergy Clin Immunol. 2024 Aug;154(2):435-446. doi: 10.1016/j.jaci.2024.03.029. Epub 2024 Jun 13. J Allergy Clin Immunol. 2024. PMID: 38878020 Free PMC article.
Transcriptional reprogramming of infiltrating neutrophils drives lung pathology in severe COVID-19 despite low viral load.
Eddins DJ, Yang J, Kosters A, Giacalone VD, Pechuan-Jorge X, Chandler JD, Eum J, Babcock BR, Dobosh BS, Hernández MR, Abdulkhader F, Collins GL, Orlova DY, Ramonell RP, Sanz I, Moussion C, Eun-Hyung Lee F, Tirouvanziam RM, Ghosn EEB. Eddins DJ, et al. Among authors: sanz i. Blood Adv. 2023 Mar 14;7(5):778-799. doi: 10.1182/bloodadvances.2022008834. Blood Adv. 2023. PMID: 36399523 Free PMC article.
Single-cell analysis of human nasal mucosal IgE antibody secreting cells reveals a newly minted phenotype.
Ramonell RP, Brown M, Woodruff MC, Levy JM, Wise SK, DelGaudio J, Duan M, Saney CL, Kyu S, Cashman KS, Hom JR, Fucile CF, Rosenberg AF, Tipton CM, Sanz I, Gibson GC, Lee FE. Ramonell RP, et al. Among authors: sanz i. Mucosal Immunol. 2023 Jun;16(3):287-301. doi: 10.1016/j.mucimm.2023.02.008. Epub 2023 Mar 15. Mucosal Immunol. 2023. PMID: 36931600 Free PMC article.
Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses.
Duan M, Nguyen DC, Joyner CJ, Saney CL, Tipton CM, Andrews J, Lonial S, Kim C, Hentenaar I, Kosters A, Ghosn E, Jackson A, Knechtle S, Maruthamuthu S, Chandran S, Martin T, Rajalingam R, Vincenti F, Breeden C, Sanz I, Gibson G, Lee FE. Duan M, et al. Among authors: sanz i. Cell Rep. 2023 Jul 25;42(7):112682. doi: 10.1016/j.celrep.2023.112682. Epub 2023 Jun 24. Cell Rep. 2023. PMID: 37355988 Free PMC article.
Poor immunogenicity upon SARS-CoV-2 mRNA vaccinations in autoimmune SLE patients is associated with pronounced EF-mediated responses and anti-BAFF/Belimumab treatment.
Faliti CE, Anam FA, Cheedarla N, Woodruff MC, Usman SY, Runnstrom MC, Van TTP, Kyu S, Ahmed H, Morrison-Porter A, Quehl H, Haddad NS, Chen W, Cheedarla S, Neish AS, Roback JD, Antia R, Khosroshahi A, Lee FE, Sanz I. Faliti CE, et al. Among authors: sanz i. medRxiv [Preprint]. 2023 Jun 12:2023.06.08.23291159. doi: 10.1101/2023.06.08.23291159. medRxiv. 2023. PMID: 37398319 Free PMC article. Preprint.
Mild antecedent COVID-19 associated with symptom-specific post-acute sequelae.
Walker TA, Truong AD, Summers A, Dixit AN, Goldstein FC, Hajjar I, Echols MR, Woodruff MC, Lee ED, Tekwani S, Carroll K, Sanz I, Lee FE, Han JE. Walker TA, et al. Among authors: sanz i. PLoS One. 2023 Jul 10;18(7):e0288391. doi: 10.1371/journal.pone.0288391. eCollection 2023. PLoS One. 2023. PMID: 37428786 Free PMC article.
Systems biology of B cells in COVID-19.
Woodruff MC, Faliti CE, Sanz I. Woodruff MC, et al. Among authors: sanz i. Semin Immunol. 2024 Mar;72:101875. doi: 10.1016/j.smim.2024.101875. Epub 2024 Mar 14. Semin Immunol. 2024. PMID: 38489999 Review.
Differentiation of Prior SARS-CoV-2 Infection and Postacute Sequelae by Standard Clinical Laboratory Measurements in the RECOVER Cohort.
Erlandson KM, Geng LN, Selvaggi CA, Thaweethai T, Chen P, Erdmann NB, Goldman JD, Henrich TJ, Hornig M, Karlson EW, Katz SD, Kim C, Cribbs SK, Laiyemo AO, Letts R, Lin JY, Marathe J, Parthasarathy S, Patterson TF, Taylor BD, Duffy ER, Haack M, Julg B, Maranga G, Hernandez C, Singer NG, Han J, Pemu P, Brim H, Ashktorab H, Charney AW, Wisnivesky J, Lin JJ, Chu HY, Go M, Singh U, Levitan EB, Goepfert PA, Nikolich JŽ, Hsu H, Peluso MJ, Kelly JD, Okumura MJ, Flaherman VJ, Quigley JG, Krishnan JA, Scholand MB, Hess R, Metz TD, Costantine MM, Rouse DJ, Taylor BS, Goldberg MP, Marshall GD, Wood J, Warren D, Horwitz L, Foulkes AS, McComsey GA; RECOVER-Adult Cohort. Erlandson KM, et al. Ann Intern Med. 2024 Sep;177(9):1209-1221. doi: 10.7326/M24-0737. Epub 2024 Aug 13. Ann Intern Med. 2024. PMID: 39133923 Free article.
Interleukin-2-secreting T helper cells promote extra-follicular B cell maturation via intrinsic regulation of a B cell mTOR-AKT-Blimp-1 axis.
Faliti CE, Mesina M, Choi J, Bélanger S, Marshall MA, Tipton CM, Hicks S, Chappa P, Cardenas MA, Abdel-Hakeem M, Thinnes TC, Cottrell C, Scharer CD, Schief WR, Nemazee D, Woodruff MC, Lindner JM, Sanz I, Crotty S. Faliti CE, et al. Among authors: sanz i. Immunity. 2024 Dec 10;57(12):2772-2789.e8. doi: 10.1016/j.immuni.2024.11.006. Epub 2024 Nov 28. Immunity. 2024. PMID: 39612915
Human Bone Marrow Plasma Cell Atlas: Maturation and Survival Pathways Unraveled by Single Cell Analyses.
Duan M, Nguyen DC, Joyner CJ, Saney CL, Tipton CM, Andrews J, Lonial S, Kim C, Hentenaar I, Kosters A, Ghosn E, Jackson A, Knechtle S, Maruthamuthu S, Chandran S, Martin T, Rajalingam R, Vincenti F, Breeden C, Sanz I, Gibson G, Eun-Hyung Lee F. Duan M, et al. Among authors: sanz i. bioRxiv [Preprint]. 2023 Jan 20:2023.01.18.524601. doi: 10.1101/2023.01.18.524601. bioRxiv. 2023. Update in: Cell Rep. 2023 Jul 25;42(7):112682. doi: 10.1016/j.celrep.2023.112682 PMID: 36711623 Free PMC article. Updated. Preprint.
323 results