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Deoxyuridine-rich cytoplasmic DNA antagonizes STING-dependent innate immune responses and sensitizes resistant tumors to anti-PD-L1 therapy.
Pandya P, Vendetti FP, El-Ghoubaira J, Pathak S, Deppas JJ, Jones R, Columbus AV, Zhang Y, Ivanov D, Huang Z, MacDonald KM, Harding SM, Buj R, Aird KM, Beumer JH, Sobol RW, Bakkenist CJ. Pandya P, et al. Among authors: sobol rw. bioRxiv [Preprint]. 2024 Apr 5:2024.04.04.588079. doi: 10.1101/2024.04.04.588079. bioRxiv. 2024. PMID: 38883769 Free PMC article. Preprint.
TRIP12 governs DNA Polymerase β involvement in DNA damage response and repair.
Inanc B, Fang Q, Andrews JF, Zeng X, Clark J, Li J, Dey NB, Ibrahim M, Sykora P, Yu Z, Braganza A, Verheij M, Jonkers J, Yates NA, Vens C, Sobol RW. Inanc B, et al. Among authors: sobol rw. bioRxiv [Preprint]. 2024 Apr 10:2024.04.08.588474. doi: 10.1101/2024.04.08.588474. bioRxiv. 2024. PMID: 38645048 Free PMC article. Preprint.
Poly-ADP-ribosylation dynamics, signaling, and analysis.
Al-Rahahleh RQ, Sobol RW. Al-Rahahleh RQ, et al. Among authors: sobol rw. Environ Mol Mutagen. 2024 Nov;65(9):315-337. doi: 10.1002/em.22623. Epub 2024 Sep 2. Environ Mol Mutagen. 2024. PMID: 39221603 Review.
Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhances alkylating agent and PARG inhibition induced cytotoxicity.
Saville KM, Al-Rahahleh RQ, Siddiqui AH, Andrews ME, Roos WP, Koczor CA, Andrews JF, Hayat F, Migaud ME, Sobol RW. Saville KM, et al. Among authors: sobol rw. DNA Repair (Amst). 2024 Aug;140:103700. doi: 10.1016/j.dnarep.2024.103700. Epub 2024 Jun 4. DNA Repair (Amst). 2024. PMID: 38897003 Free article.
Protein lipoylation: mitochondria, cuproptosis, and beyond.
Lin CH, Chin Y, Zhou M, Sobol RW, Hung MC, Tan M. Lin CH, et al. Among authors: sobol rw. Trends Biochem Sci. 2024 Aug;49(8):729-744. doi: 10.1016/j.tibs.2024.04.002. Epub 2024 May 6. Trends Biochem Sci. 2024. PMID: 38714376 Review.
151 results