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A small-molecule microtubule-stabilizing agent safely reduces Aβ plaque and tau pathology in transgenic mouse models of Alzheimer's disease.
Yao Y, Muench M, Alle T, Zhang B, Lucero B, Perez-Tremble R, McGrosso D, Newman M, Gonzalez DJ, Lee VM, Ballatore C, Brunden KR. Yao Y, et al. Among authors: perez tremble r. Alzheimers Dement. 2024 Jul;20(7):4540-4558. doi: 10.1002/alz.13875. Epub 2024 Jun 17. Alzheimers Dement. 2024. PMID: 38884283 Free PMC article.
Hypnotic treatment improves sleep architecture and EEG disruptions and rescues memory deficits in a mouse model of fragile X syndrome.
Martinez JD, Wilson LG, Brancaleone WP, Peterson KG, Popke DS, Garzon VC, Perez Tremble RE, Donnelly MJ, Mendez Ortega SL, Torres D, Shaver JJ, Jiang S, Yang Z, Aton SJ. Martinez JD, et al. Among authors: perez tremble re. Cell Rep. 2024 Jun 25;43(6):114266. doi: 10.1016/j.celrep.2024.114266. Epub 2024 May 23. Cell Rep. 2024. PMID: 38787724 Free article.
Hypnotic treatment reverses NREM sleep disruption and EEG desynchronization in a mouse model of Fragile X syndrome to rescue memory consolidation deficits.
Martinez JD, Wilson LG, Brancaleone WP, Peterson KG, Popke DS, Garzon VC, Perez Tremble RE, Donnelly MJ, Mendez Ortega SL, Torres D, Shaver JJ, Clawson BC, Jiang S, Yang Z, Aton SJ. Martinez JD, et al. Among authors: perez tremble re. bioRxiv [Preprint]. 2023 Jul 18:2023.07.14.549070. doi: 10.1101/2023.07.14.549070. bioRxiv. 2023. PMID: 37502832 Free PMC article. Preprint.