Matsuzaki T - Search Results

1

Minimal Involvement of P-gp and BCRP in Oral Absorption of Ensitrelvir, An Oral SARS-CoV-2 3C-like Protease Inhibitor, in a Non-Clinical Investigation.

Watari R, Tamura N, Yoshida S, Kido Y, Matsuzaki T. Watari R, et al. Among authors: matsuzaki t. J Pharm Sci. 2024 Sep;113(9):2871-2878. doi: 10.1016/j.xphs.2024.06.009. Epub 2024 Jun 15. J Pharm Sci. 2024. PMID: 38885812

2

Utility of Coproporphyrin-I Determination in First-in-Human Study for Early Evaluation of OATP1B Inhibitory Potential Based on Investigation of Ensitrelvir, an Oral SARS-CoV-2 3C-Like Protease Inhibitor.

Watari R, Sawada H, Hashimoto H, Kasai Y, Oka R, Shimizu R, Matsuzaki T. Watari R, et al. Among authors: matsuzaki t. J Pharm Sci. 2024 Mar;113(3):798-805. doi: 10.1016/j.xphs.2023.09.016. Epub 2023 Sep 23. J Pharm Sci. 2024. PMID: 37742997

3

Prediction of drug-drug interaction risk of P-glycoprotein substrate in drug discovery.

Kido Y, Nanchi I, Matsuzaki T, Watari R, Kiyohara H, Seki N, Okuda T. Kido Y, et al. Among authors: matsuzaki t. Drug Metab Pharmacokinet. 2024 Jun;56:101008. doi: 10.1016/j.dmpk.2024.101008. Epub 2024 Mar 11. Drug Metab Pharmacokinet. 2024. PMID: 38663183

4

Species difference in brain penetration of P-gp and BCRP substrates among monkey, dog and mouse.

Kido Y, Nanchi I, Fusamae Y, Matsuzaki T, Akazawa T, Sawada H, Iwasaki M, Nishida K, Tsuchiya E, Okuda T. Kido Y, et al. Among authors: matsuzaki t. Drug Metab Pharmacokinet. 2022 Feb;42:100426. doi: 10.1016/j.dmpk.2021.100426. Epub 2021 Oct 23. Drug Metab Pharmacokinet. 2022. PMID: 34974334

5

The antagonistic activity profile of naloxone in μ-opioid receptor agonist-induced psychological dependence.

Nakamura A, Yasufuku K, Shimada S, Aritomi H, Furue Y, Chiba H, Muramoto M, Takase K, Koike K, Matsumoto T, Shimada T, Watari R, Matsuzaki T, Asaki T, Kanemasa T, Fujita M. Nakamura A, et al. Among authors: matsuzaki t. Neurosci Lett. 2020 Sep 14;735:135177. doi: 10.1016/j.neulet.2020.135177. Epub 2020 Jun 20. Neurosci Lett. 2020. PMID: 32569809 Free article.

6

Improved Human Pharmacokinetic Prediction of Hepatically Metabolized Drugs With Species-Specific Systemic Clearance.

Horiuchi K, Ohnishi S, Matsuzaki T, Funaki S, Watanabe A, Mizutare T, Matsumoto S, Nezasa KI, Hasegawa H. Horiuchi K, et al. Among authors: matsuzaki t. J Pharm Sci. 2018 May;107(5):1443-1453. doi: 10.1016/j.xphs.2017.12.027. Epub 2018 Jan 10. J Pharm Sci. 2018. PMID: 29331382

7

Evaluation of Drug-Drug Interactions of Ensitrelvir, a SARS-CoV-2 3CL Protease Inhibitor, With Transporter Substrates Based on In Vitro and Clinical Studies.

Shimizu R, Matsuzaki T, Oka R, Sonoyama T, Fukuhara T, Kuwata A, Matsuo Y, Kubota R. Shimizu R, et al. Among authors: matsuzaki t. J Clin Pharmacol. 2023 Aug;63(8):918-927. doi: 10.1002/jcph.2247. Epub 2023 May 10. J Clin Pharmacol. 2023. PMID: 37043676

8

Evaluation of the Drug-Drug Interaction Potential of Ensitrelvir Fumaric Acid with Cytochrome P450 3A Substrates in Healthy Japanese Adults.

Shimizu R, Sonoyama T, Fukuhara T, Kuwata A, Matsuzaki T, Matsuo Y, Kubota R. Shimizu R, et al. Among authors: matsuzaki t. Clin Drug Investig. 2023 May;43(5):335-346. doi: 10.1007/s40261-023-01265-8. Epub 2023 May 12. Clin Drug Investig. 2023. PMID: 37171749 Free PMC article. Clinical Trial.

9

Preventive effects of naldemedine, peripherally acting μ-opioid receptor antagonist, on morphine-induced nausea and vomiting in ferrets.

Kanemasa T, Matsuzaki T, Koike K, Hasegawa M, Suzuki T. Kanemasa T, et al. Among authors: matsuzaki t. Life Sci. 2020 Sep 15;257:118048. doi: 10.1016/j.lfs.2020.118048. Epub 2020 Jul 2. Life Sci. 2020. PMID: 32622946 Free article.

10

The antiviral effects of baloxavir marboxil against influenza A virus infection in ferrets.

Kitano M, Matsuzaki T, Oka R, Baba K, Noda T, Yoshida Y, Sato K, Kiyota K, Mizutare T, Yoshida R, Sato A, Kamimori H, Shishido T, Naito A. Kitano M, et al. Among authors: matsuzaki t. Influenza Other Respir Viruses. 2020 Nov;14(6):710-719. doi: 10.1111/irv.12760. Epub 2020 Jun 13. Influenza Other Respir Viruses. 2020. PMID: 32533654 Free PMC article.

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