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A dual-acting DNASE1/DNASE1L3 biologic prevents autoimmunity and death in genetic and induced lupus models.
Stabach PR, Sims D, Gomez-Bañuelos E, Zehentmeier S, Dammen-Brower K, Bernhisel A, Kujawski S, Lopez SG, Petri M, Goldman DW, Lester ER, Le Q, Ishaq T, Kim H, Srivastava S, Kumar D, Pereira JP, Yarema KJ, Koumpouras F, Andrade F, Braddock DT. Stabach PR, et al. Among authors: braddock dt. JCI Insight. 2024 Jun 18;9(14):e177003. doi: 10.1172/jci.insight.177003. JCI Insight. 2024. PMID: 38888971 Free PMC article.
Novel treatment for PXE: Recombinant ENPP1 enzyme therapy.
Jacobs IJ, Obiri-Yeboah D, Stabach PR, Braddock DT, Li Q. Jacobs IJ, et al. Among authors: braddock dt. Mol Ther. 2024 Nov 6;32(11):3815-3820. doi: 10.1016/j.ymthe.2024.09.028. Epub 2024 Sep 27. Mol Ther. 2024. PMID: 39342427
Effect of Mutation Type on Ectopic Ossification Among Adult Patients With X-Linked Hypophosphatemia.
Kato H, Ishihara Y, Ohata Y, Irie K, Watanabe S, Kimura S, Hoshino Y, Hidaka N, Kinoshita Y, Taniguchi Y, Kobayashi H, Braddock DT, Kubota T, Ozono K, Nangaku M, Makita N, Ito N. Kato H, et al. Among authors: braddock dt. J Endocr Soc. 2024 Oct 22;8(12):bvae184. doi: 10.1210/jendso/bvae184. eCollection 2024 Oct 29. J Endocr Soc. 2024. PMID: 39498416 Free PMC article.
Catalysis-Independent ENPP1 Protein Signaling Regulates Mammalian Bone Mass.
Zimmerman K, Liu X, von Kroge S, Stabach P, Lester ER, Chu EY, Srivastava S, Somerman MJ, Tommasini SM, Busse B, Schinke T, Carpenter TO, Oheim R, Braddock DT. Zimmerman K, et al. Among authors: braddock dt. J Bone Miner Res. 2022 Sep;37(9):1733-1749. doi: 10.1002/jbmr.4640. Epub 2022 Jul 29. J Bone Miner Res. 2022. PMID: 35773783 Free PMC article.
48 results