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Preclinical evidence for the use of anti-Trop-2 antibody-drug conjugate Sacituzumab govitecan in cerebral metastasized castration-resistant prostate cancer.
Weiten R, Niemann M, Below E, Friker LL, Ralser DJ, Toma M, Kristiansen G, Hahn O, Zechel S, Grünwald V, Bald T, Siewert J, Pietsch T, Ritter M, Hölzel M, Eckstein M, Alajati A, Krausewitz P, Klümper N. Weiten R, et al. Among authors: bald t. Cancer Med. 2024 Jun;13(12):e7320. doi: 10.1002/cam4.7320. Cancer Med. 2024. PMID: 38895886 Free PMC article.
CD155 loss enhances tumor suppression via combined host and tumor-intrinsic mechanisms.
Li XY, Das I, Lepletier A, Addala V, Bald T, Stannard K, Barkauskas D, Liu J, Aguilera AR, Takeda K, Braun M, Nakamura K, Jacquelin S, Lane SW, Teng MW, Dougall WC, Smyth MJ. Li XY, et al. Among authors: bald t. J Clin Invest. 2022 Mar 15;132(6):e159825. doi: 10.1172/JCI159825. J Clin Invest. 2022. PMID: 35289314 Free PMC article. No abstract available.
Innate Cancer Immunoediting.
Bald T, Smyth MJ. Bald T, et al. J Invest Dermatol. 2020 Apr;140(4):745-747. doi: 10.1016/j.jid.2019.09.015. J Invest Dermatol. 2020. PMID: 32200878 Free article.
BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection.
Mills RJ, Humphrey SJ, Fortuna PRJ, Lor M, Foster SR, Quaife-Ryan GA, Johnston RL, Dumenil T, Bishop C, Rudraraju R, Rawle DJ, Le T, Zhao W, Lee L, Mackenzie-Kludas C, Mehdiabadi NR, Halliday C, Gilham D, Fu L, Nicholls SJ, Johansson J, Sweeney M, Wong NCW, Kulikowski E, Sokolowski KA, Tse BWC, Devilée L, Voges HK, Reynolds LT, Krumeich S, Mathieson E, Abu-Bonsrah D, Karavendzas K, Griffen B, Titmarsh D, Elliott DA, McMahon J, Suhrbier A, Subbarao K, Porrello ER, Smyth MJ, Engwerda CR, MacDonald KPA, Bald T, James DE, Hudson JE. Mills RJ, et al. Among authors: bald t. Cell. 2021 Apr 15;184(8):2167-2182.e22. doi: 10.1016/j.cell.2021.03.026. Epub 2021 Mar 16. Cell. 2021. PMID: 33811809 Free PMC article.
The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation.
Ng SS, De Labastida Rivera F, Yan J, Corvino D, Das I, Zhang P, Kuns R, Chauhan SB, Hou J, Li XY, Frame TCM, McEnroe BA, Moore E, Na J, Engel JA, Soon MSF, Singh B, Kueh AJ, Herold MJ, Montes de Oca M, Singh SS, Bunn PT, Aguilera AR, Casey M, Braun M, Ghazanfari N, Wani S, Wang Y, Amante FH, Edwards CL, Haque A, Dougall WC, Singh OP, Baxter AG, Teng MWL, Loukas A, Daly NL, Cloonan N, Degli-Esposti MA, Uzonna J, Heath WR, Bald T, Tey SK, Nakamura K, Hill GR, Kumar R, Sundar S, Smyth MJ, Engwerda CR. Ng SS, et al. Among authors: bald t. Nat Immunol. 2020 Oct;21(10):1205-1218. doi: 10.1038/s41590-020-0758-6. Epub 2020 Aug 24. Nat Immunol. 2020. PMID: 32839608 Free PMC article.
Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes.
Reuten R, Patel TR, McDougall M, Rama N, Nikodemus D, Gibert B, Delcros JG, Prein C, Meier M, Metzger S, Zhou Z, Kaltenberg J, McKee KK, Bald T, Tüting T, Zigrino P, Djonov V, Bloch W, Clausen-Schaumann H, Poschl E, Yurchenco PD, Ehrbar M, Mehlen P, Stetefeld J, Koch M. Reuten R, et al. Among authors: bald t. Nat Commun. 2016 Nov 30;7:13515. doi: 10.1038/ncomms13515. Nat Commun. 2016. PMID: 27901020 Free PMC article.
TGFβ shuts the door on T cells.
Bald T, Smyth MJ. Bald T, et al. Br J Cancer. 2018 Jul;119(1):1-3. doi: 10.1038/s41416-018-0122-x. Epub 2018 Jun 14. Br J Cancer. 2018. PMID: 29899392 Free PMC article.
75 results