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Severe Combined Immunodeficiency from a Homozygous DNA Ligase 1 Mutant with Reduced Catalytic Activity but Increased Ligation Fidelity.
Alajlan H, Raducanu VS, Lopez de Los Santos Y, Tehseen M, Alruwaili H, Al-Mazrou A, Mohammad R, Al-Alwan M, De Biasio A, Merzaban JS, Al-Mousa H, Hamdan SM, Alazami AM. Alajlan H, et al. Among authors: de biasio a. J Clin Immunol. 2024 Jun 19;44(7):151. doi: 10.1007/s10875-024-01754-1. J Clin Immunol. 2024. PMID: 38896336 Free PMC article.
Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Blair K, Tehseen M, Raducanu VS, Shahid T, Lancey C, Rashid F, Crehuet R, Hamdan SM, De Biasio A. Blair K, et al. Among authors: de biasio a. Nat Commun. 2022 Dec 20;13(1):7833. doi: 10.1038/s41467-022-35475-z. Nat Commun. 2022. PMID: 36539424 Free PMC article.
Cryo-EM structure of human Pol κ bound to DNA and mono-ubiquitylated PCNA.
Lancey C, Tehseen M, Bakshi S, Percival M, Takahashi M, Sobhy MA, Raducanu VS, Blair K, Muskett FW, Ragan TJ, Crehuet R, Hamdan SM, De Biasio A. Lancey C, et al. Among authors: de biasio a. Nat Commun. 2021 Oct 19;12(1):6095. doi: 10.1038/s41467-021-26251-6. Nat Commun. 2021. PMID: 34667155 Free PMC article.
39 results