Lespine A - Search Results

1

Target repurposing unravels avermectins and derivatives as novel antibiotics inhibiting energy-coupling factor transporters (ECFTs).

Haupenthal J, Rafehi M, Kany AM, Lespine A, Stefan K, Hirsch AKH, Stefan SM. Haupenthal J, et al. Among authors: lespine a. Arch Pharm (Weinheim). 2024 Sep;357(9):e2400267. doi: 10.1002/ardp.202400267. Epub 2024 Jun 19. Arch Pharm (Weinheim). 2024. PMID: 38896404

2

A Large Impact of Obesity on the Disposition of Ivermectin, Moxidectin and Eprinomectin in a Canine Model: Relevance for COVID-19 Patients.

Bousquet-Mélou A, Lespine A, Sutra JF, Bargues I, Toutain PL. Bousquet-Mélou A, et al. Among authors: lespine a. Front Pharmacol. 2021 May 20;12:666348. doi: 10.3389/fphar.2021.666348. eCollection 2021. Front Pharmacol. 2021. PMID: 34093195 Free PMC article.

3

Moxidectin and the avermectins: Consanguinity but not identity.

Prichard R, Ménez C, Lespine A. Prichard R, et al. Among authors: lespine a. Int J Parasitol Drugs Drug Resist. 2012 Apr 14;2:134-53. doi: 10.1016/j.ijpddr.2012.04.001. eCollection 2012 Dec. Int J Parasitol Drugs Drug Resist. 2012. PMID: 24533275 Free PMC article. Review.

4

The transcription factor NHR-8: A new target to increase ivermectin efficacy in nematodes.

Ménez C, Alberich M, Courtot E, Guegnard F, Blanchard A, Aguilaniu H, Lespine A. Ménez C, et al. Among authors: lespine a. PLoS Pathog. 2019 Feb 13;15(2):e1007598. doi: 10.1371/journal.ppat.1007598. eCollection 2019 Feb. PLoS Pathog. 2019. PMID: 30759156 Free PMC article.

5

Genetic polymorphism, constitutive expression and tissue localization of Dirofilaria immitis P-glycoprotein 11: a putative marker of macrocyclic lactone resistance.

Curry E, Prichard R, Lespine A. Curry E, et al. Among authors: lespine a. Parasit Vectors. 2022 Dec 21;15(1):482. doi: 10.1186/s13071-022-05571-6. Parasit Vectors. 2022. PMID: 36544229 Free PMC article.

6

In silico analysis of the binding of anthelmintics to Caenorhabditis elegansP-glycoprotein 1.

David MA, Orlowski S, Prichard RK, Hashem S, André F, Lespine A. David MA, et al. Among authors: lespine a. Int J Parasitol Drugs Drug Resist. 2016 Dec;6(3):299-313. doi: 10.1016/j.ijpddr.2016.09.001. Epub 2016 Sep 15. Int J Parasitol Drugs Drug Resist. 2016. PMID: 27746191 Free PMC article.

7

P-glycoproteins and other multidrug resistance transporters in the pharmacology of anthelmintics: Prospects for reversing transport-dependent anthelmintic resistance.

Lespine A, Ménez C, Bourguinat C, Prichard RK. Lespine A, et al. Int J Parasitol Drugs Drug Resist. 2011 Nov 7;2:58-75. doi: 10.1016/j.ijpddr.2011.10.001. eCollection 2012 Dec. Int J Parasitol Drugs Drug Resist. 2011. PMID: 24533264 Free PMC article. Review.

8

P-glycoproteins play a role in ivermectin resistance in cyathostomins.

Peachey LE, Pinchbeck GL, Matthews JB, Burden FA, Lespine A, von Samson-Himmelstjerna G, Krücken J, Hodgkinson JE. Peachey LE, et al. Among authors: lespine a. Int J Parasitol Drugs Drug Resist. 2017 Dec;7(3):388-398. doi: 10.1016/j.ijpddr.2017.10.006. Epub 2017 Oct 25. Int J Parasitol Drugs Drug Resist. 2017. PMID: 29121562 Free PMC article.

9

Role of P-glycoprotein in the disposition of macrocyclic lactones: A comparison between ivermectin, eprinomectin, and moxidectin in mice.

Kiki-Mvouaka S, Ménez C, Borin C, Lyazrhi F, Foucaud-Vignault M, Dupuy J, Collet X, Alvinerie M, Lespine A. Kiki-Mvouaka S, et al. Among authors: lespine a. Drug Metab Dispos. 2010 Apr;38(4):573-80. doi: 10.1124/dmd.109.030700. Epub 2010 Jan 20. Drug Metab Dispos. 2010. PMID: 20089736

10

Acquired Tolerance to Ivermectin and Moxidectin after Drug Selection Pressure in the Nematode Caenorhabditis elegans.

Ménez C, Alberich M, Kansoh D, Blanchard A, Lespine A. Ménez C, et al. Among authors: lespine a. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4809-19. doi: 10.1128/AAC.00713-16. Print 2016 Aug. Antimicrob Agents Chemother. 2016. PMID: 27246778 Free PMC article.

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