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Structure-Based Design of a Lead Compound Derived from Natural Schweinfurthins with Antitumor Properties That Target Oxysterol-Binding Protein.
Jézéquel G, Rampal C, Guimard C, Kovacs D, Polidori J, Bigay J, Bignon J, Askenatzis L, Litaudon M, Pham VC, Huong DTM, Nguyen AL, Pruvost A, Virolle T, Mesmin B, Desrat S, Antonny B, Roussi F. Jézéquel G, et al. Among authors: pham vc. J Med Chem. 2023 Oct 26;66(20):14208-14220. doi: 10.1021/acs.jmedchem.3c01298. Epub 2023 Oct 5. J Med Chem. 2023. PMID: 37795600
Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function.
Jézéquel G, Grimanelli Z, Guimard C, Bigay J, Haddad J, Bignon J, Apel C, Steinmetz V, Askenatzis L, Levaïque H, Pradelli C, Pham VC, Huong DTM, Litaudon M, Gautier R, El Kalamouni C, Antonny B, Desrat S, Mesmin B, Roussi F. Jézéquel G, et al. Among authors: pham vc. J Med Chem. 2025 Jan 9;68(1):196-211. doi: 10.1021/acs.jmedchem.4c01705. Epub 2024 Dec 20. J Med Chem. 2025. PMID: 39704626
Epigenetic regulation by polycomb repressive complex 1 promotes cerebral cavernous malformations.
Pham VC, Rödel CJ, Valentino M, Malinverno M, Paolini A, Münch J, Pasquier C, Onyeogaziri FC, Lazovic B, Girard R, Koskimäki J, Hußmann M, Keith B, Jachimowicz D, Kohl F, Hagelkruys A, Penninger JM, Schulte-Merker S, Awad IA, Hicks R, Magnusson PU, Faurobert E, Pagani M, Abdelilah-Seyfried S. Pham VC, et al. EMBO Mol Med. 2024 Nov;16(11):2827-2855. doi: 10.1038/s44321-024-00152-9. Epub 2024 Oct 14. EMBO Mol Med. 2024. PMID: 39402138 Free PMC article.
ATF6 Promotes Colorectal Cancer Growth and Stemness by Regulating the Wnt Pathway.
Rodvold JJ, Grimmer M, Ruiz K, Marsters SA, Oikonomidi I, Tan-Aristy E, Pham VC, Sarkar T, Harnoss JM, Shatz-Binder W, Modrusan ZD, Wu TD, Lill JR, Villemure E, Rudolph J, de Sousa E Melo F, Ashkenazi A. Rodvold JJ, et al. Among authors: pham vc. Cancer Res Commun. 2024 Oct 1;4(10):2734-2755. doi: 10.1158/2767-9764.CRC-24-0268. Cancer Res Commun. 2024. PMID: 39324706 Free PMC article.
95 results