Greig I - Search Results

1

Fluorinated perhexiline derivative attenuates vascular proliferation in pulmonary arterial hypertension smooth muscle cells.

Griffiths K, Grand RJ, Horan I, Certo M, Keeler RC, Mauro C, Tseng CC, Greig I, Morrell NW, Zanda M, Frenneaux MP, Madhani M. Griffiths K, et al. Among authors: greig i. Vascul Pharmacol. 2024 Sep;156:107399. doi: 10.1016/j.vph.2024.107399. Epub 2024 Jun 18. Vascul Pharmacol. 2024. PMID: 38901807 Free article.

2

The atypical 'hippocampal' glutamate receptor coupled to phospholipase D that controls stretch-sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2.

Thompson KJ, Watson S, Zanato C, Dall'Angelo S, De Nooij JC, Pace-Bonello B, Shenton FC, Sanger HE, Heinz BA, Broad LM, Grosjean N, McQuillian JR, Dubini M, Pyner S, Greig I, Zanda M, Bleakman D, Banks RW, Bewick GS. Thompson KJ, et al. Among authors: greig i. Exp Physiol. 2024 Jan;109(1):81-99. doi: 10.1113/EP090761. Epub 2023 Sep 1. Exp Physiol. 2024. PMID: 37656490 Free PMC article. Review.

3

Small-molecule targeting AMPA-mediated excitotoxicity has therapeutic effects in mouse models for multiple sclerosis.

Zhai D, Yan S, Samsom J, Wang L, Su P, Jiang A, Zhang H, Jia Z, Wallach I, Heifets A, Zanato C, Tseng CC, Wong AHC, Greig IR, Liu F. Zhai D, et al. Among authors: greig ir. Sci Adv. 2023 Dec 8;9(49):eadj6187. doi: 10.1126/sciadv.adj6187. Epub 2023 Dec 8. Sci Adv. 2023. PMID: 38064562 Free PMC article.

4

Author Correction: AI is a viable alternative to high throughput screening: a 318-target study.

Atomwise AIMS Program. Atomwise AIMS Program. Sci Rep. 2024 Sep 16;14(1):21579. doi: 10.1038/s41598-024-70321-w. Sci Rep. 2024. PMID: 39284864 Free PMC article. No abstract available.

5

Positive allosteric modulation of the cannabinoid CB₁ receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics.

Green HM, Manning JJ, Greig IR, Ross RA, Finlay DB, Glass M. Green HM, et al. Among authors: greig ir. Br J Pharmacol. 2024 Oct;181(19):3642-3662. doi: 10.1111/bph.16433. Epub 2024 Jun 3. Br J Pharmacol. 2024. PMID: 38831545

6

CB1 Receptor Negative Allosteric Modulators as a Potential Tool to Reverse Cannabinoid Toxicity.

Flavin A, Azizi P, Murataeva N, Yust K, Du W, Ross R, Greig I, Nguyen T, Zhang Y, Mackie K, Straiker A. Flavin A, et al. Among authors: greig i. Molecules. 2024 Apr 20;29(8):1881. doi: 10.3390/molecules29081881. Molecules. 2024. PMID: 38675703 Free PMC article.

7

AI is a viable alternative to high throughput screening: a 318-target study.

Atomwise AIMS Program. Atomwise AIMS Program. Sci Rep. 2024 Apr 2;14(1):7526. doi: 10.1038/s41598-024-54655-z. Sci Rep. 2024. PMID: 38565852 Free PMC article.

8

In Vitro Characterization of 6-Methyl-3-(2-nitro-1-(thiophen-2-yl)ethyl)-2-phenyl-1H-indole (ZCZ011) at the Type 1 Cannabinoid Receptor: Allosteric Agonist or Allosteric Modulator?

Green HM, Finlay DB, Ross RA, Greig IR, Duffull SB, Glass M. Green HM, et al. Among authors: greig ir. ACS Pharmacol Transl Sci. 2022 Nov 22;5(12):1279-1291. doi: 10.1021/acsptsci.2c00160. eCollection 2022 Dec 9. ACS Pharmacol Transl Sci. 2022. PMID: 36524007 Free PMC article.

9

Motor-like Tics are Mediated by CB₂ Cannabinoid Receptor-dependent and Independent Mechanisms Associated with Age and Sex.

Gorberg V, Borisov V, Greig IR, Pertwee RG, McCaffery P, Anavi-Goffer S. Gorberg V, et al. Among authors: greig ir. Mol Neurobiol. 2022 Aug;59(8):5070-5083. doi: 10.1007/s12035-022-02884-6. Epub 2022 Jun 6. Mol Neurobiol. 2022. PMID: 35666403 Free PMC article.

10

Antidepressant activity of pharmacological and genetic deactivation of the small-conductance calcium-activated potassium channel subtype-3.

Nashed MG, Waye S, Hasan SMN, Nguyen D, Wiseman M, Zhang J, Lau H, Dinesh OC, Raymond R, Greig IR, Bambico FR, Nobrega JN. Nashed MG, et al. Among authors: greig ir. Psychopharmacology (Berl). 2022 Jan;239(1):253-266. doi: 10.1007/s00213-021-06045-w. Epub 2022 Jan 4. Psychopharmacology (Berl). 2022. PMID: 34982171

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