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The lipopolysaccharide-TLR4 axis regulates hepatic glutaminase 1 expression promoting liver ammonia build-up as steatotic liver disease progresses to steatohepatitis.
Mercado-Gómez M, Goikoetxea-Usandizaga N, Kerbert AJC, Gracianteparaluceta LU, Serrano-Maciá M, Lachiondo-Ortega S, Rodriguez-Agudo R, Gil-Pitarch C, Simón J, González-Recio I, Fondevila MF, Santamarina-Ojeda P, Fraga MF, Nogueiras R, Heras JL, Jalan R, Martínez-Chantar ML, Delgado TC. Mercado-Gómez M, et al. Among authors: gracianteparaluceta lu. Metabolism. 2024 Sep;158:155952. doi: 10.1016/j.metabol.2024.155952. Epub 2024 Jun 19. Metabolism. 2024. PMID: 38906371 Free article.