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Nuclear Smooth Muscle α-actin Participates in Vascular Smooth Muscle Cell Differentiation.
Kwartler CS, Pedroza AJ, Kaw A, Guan P, Ma S, Duan XY, Kernell C, Wang C, Pinelo JEE, Bowen MSB, Chen J, Zhong Y, Sinha S, Shen X, Fischbein MP, Milewicz DM. Kwartler CS, et al. Among authors: duan xy. Nat Cardiovasc Res. 2023 Oct;2(10):937-955. doi: 10.1038/s44161-023-00337-4. Epub 2023 Sep 28. Nat Cardiovasc Res. 2023. PMID: 38919852 Free PMC article.
Nuclear Smooth Muscle α-actin in Vascular Smooth Muscle Cell Differentiation.
Kwartler CS, Pedroza AJ, Kaw A, Guan P, Ma S, Duan XY, Kernell C, Wang C, Pinelo JEE, Borthwick MS, Chen J, Zhong Y, Sinha S, Shen X, Fischbein MP, Milewicz DM. Kwartler CS, et al. Among authors: duan xy. Res Sq [Preprint]. 2023 Feb 28:rs.3.rs-1623114. doi: 10.21203/rs.3.rs-1623114/v1. Res Sq. 2023. PMID: 36909460 Free PMC article. Updated. Preprint.
Resistance of Acta2R149C/+ mice to aortic disease is associated with defective release of mutant smooth muscle α-actin from the chaperonin-containing TCP1 folding complex.
Chen J, Kaw K, Lu H, Fagnant PM, Chattopadhyay A, Duan XY, Zhou Z, Ma S, Liu Z, Huang J, Kamm K, Stull JT, Kwartler CS, Trybus KM, Milewicz DM. Chen J, et al. Among authors: duan xy. J Biol Chem. 2021 Dec;297(6):101228. doi: 10.1016/j.jbc.2021.101228. Epub 2021 Oct 1. J Biol Chem. 2021. PMID: 34600884 Free PMC article.
Augmenting Mitochondrial Respiration in Immature Smooth Muscle Cells with an ACTA2 Pathogenic Variant Mitigates Moyamoya-like Cerebrovascular Disease.
Kaw A, Wu T, Starosolski Z, Zhou Z, Pedroza AJ, Majumder S, Duan X, Kaw K, Pinelo JEE, Fischbein MP, Lorenzi PL, Tan L, Martinez SA, Mahmud I, Devkota L, Taegtmeyer H, Ghaghada KB, Marrelli SP, Kwartler CS, Milewicz DM. Kaw A, et al. Res Sq [Preprint]. 2023 Oct 12:rs.3.rs-3304679. doi: 10.21203/rs.3.rs-3304679/v1. Res Sq. 2023. PMID: 37886459 Free PMC article. Preprint.
Loss-of-Function Mutations in YY1AP1 Lead to Grange Syndrome and a Fibromuscular Dysplasia-Like Vascular Disease.
Guo DC, Duan XY, Regalado ES, Mellor-Crummey L, Kwartler CS, Kim D, Lieberman K, de Vries BBA, Pfundt R, Schinzel A, Kotzot D, Shen X, Yang ML; University of Washington Center for Mendelian Genomics; Bamshad MJ, Nickerson DA, Gornik HL, Ganesh SK, Braverman AC, Grange DK, Milewicz DM. Guo DC, et al. Among authors: duan xy. Am J Hum Genet. 2017 Jan 5;100(1):21-30. doi: 10.1016/j.ajhg.2016.11.008. Epub 2016 Dec 8. Am J Hum Genet. 2017. PMID: 27939641 Free PMC article.
SMAD4 rare variants in individuals and families with thoracic aortic aneurysms and dissections.
Duan XY, Guo DC, Regalado ES, Shen H; University of Washington Center for Mendelian Genomics; Coselli JS, Estrera AL, Safi HJ, Bamshad MJ, Nickerson DA, LeMaire SA, De Backer J, Milewicz DM. Duan XY, et al. Eur J Hum Genet. 2019 Jul;27(7):1054-1060. doi: 10.1038/s41431-019-0357-x. Epub 2019 Feb 26. Eur J Hum Genet. 2019. PMID: 30809044 Free PMC article. Clinical Trial.
LOX Mutations Predispose to Thoracic Aortic Aneurysms and Dissections.
Guo DC, Regalado ES, Gong L, Duan X, Santos-Cortez RL, Arnaud P, Ren Z, Cai B, Hostetler EM, Moran R, Liang D, Estrera A, Safi HJ; University of Washington Center for Mendelian Genomics; Leal SM, Bamshad MJ, Shendure J, Nickerson DA, Jondeau G, Boileau C, Milewicz DM. Guo DC, et al. Circ Res. 2016 Mar 18;118(6):928-34. doi: 10.1161/CIRCRESAHA.115.307130. Epub 2016 Jan 12. Circ Res. 2016. PMID: 26838787 Free PMC article.
154 results