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Chronic linaclotide treatment reduces colitis-induced neuroplasticity and reverses persistent bladder dysfunction.
Grundy L, Harrington AM, Castro J, Garcia-Caraballo S, Deiteren A, Maddern J, Rychkov GY, Ge P, Peters S, Feil R, Miller P, Ghetti A, Hannig G, Kurtz CB, Silos-Santiago I, Brierley SM. Grundy L, et al. Among authors: deiteren a. JCI Insight. 2018 Oct 4;3(19):e121841. doi: 10.1172/jci.insight.121841. JCI Insight. 2018. PMID: 30282832 Free PMC article.
NaV1.1 inhibition can reduce visceral hypersensitivity.
Salvatierra J, Castro J, Erickson A, Li Q, Braz J, Gilchrist J, Grundy L, Rychkov GY, Deiteren A, Rais R, King GF, Slusher BS, Basbaum A, Pasricha PJ, Brierley SM, Bosmans F. Salvatierra J, et al. Among authors: deiteren a. JCI Insight. 2018 Jun 7;3(11):e121000. doi: 10.1172/jci.insight.121000. eCollection 2018 Jun 7. JCI Insight. 2018. PMID: 29875317 Free PMC article.
Contribution of membrane receptor signalling to chronic visceral pain.
Sadeghi M, Erickson A, Castro J, Deiteren A, Harrington AM, Grundy L, Adams DJ, Brierley SM. Sadeghi M, et al. Among authors: deiteren a. Int J Biochem Cell Biol. 2018 May;98:10-23. doi: 10.1016/j.biocel.2018.02.017. Epub 2018 Mar 21. Int J Biochem Cell Biol. 2018. PMID: 29477359 Review.
Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain.
Castro J, Grundy L, Deiteren A, Harrington AM, O'Donnell T, Maddern J, Moore J, Garcia-Caraballo S, Rychkov GY, Yu R, Kaas Q, Craik DJ, Adams DJ, Brierley SM. Castro J, et al. Among authors: deiteren a. Br J Pharmacol. 2018 Jun;175(12):2384-2398. doi: 10.1111/bph.14115. Epub 2018 Feb 13. Br J Pharmacol. 2018. PMID: 29194563 Free PMC article.
24 results