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A high-throughput screening identifies MCM chromatin loading inhibitors targeting cells with increased replication origins.
Falbo L, Técher H, Sannino V, Robusto M, Fagà G, Pezzimenti F, Romeo F, Colombo LG, Vultaggio S, Fancelli D, Monzani S, Cecatiello V, Pasqualato S, Varasi M, Mercurio C, Costanzo V. Falbo L, et al. Among authors: techer h. iScience. 2024 Jul 22;27(8):110567. doi: 10.1016/j.isci.2024.110567. eCollection 2024 Aug 16. iScience. 2024. PMID: 39184446 Free PMC article.
[SAMHD1 acts at stalled replication forks to prevent interferon induction].
Coquel F, Silva MJ, Técher H, Zadorozhny K, Sharma S, Nieminuszczy J, Mettling C, Dardillac E, Barthe A, Schmitz AL, Promonet A, Cribier A, Sarrazin A, Niedzwiedz W, Lopez B, Costanzo V, Krejci L, Chabes A, Benkirane M, Lin YL, Pasero P. Coquel F, et al. Among authors: techer h. C R Biol. 2020 Jun 5;343(1):9-21. doi: 10.5802/crbiol.10. C R Biol. 2020. PMID: 32720483 Free article. Review. French.
SAMHD1 acts at stalled replication forks to prevent interferon induction.
Coquel F, Silva MJ, Técher H, Zadorozhny K, Sharma S, Nieminuszczy J, Mettling C, Dardillac E, Barthe A, Schmitz AL, Promonet A, Cribier A, Sarrazin A, Niedzwiedz W, Lopez B, Costanzo V, Krejci L, Chabes A, Benkirane M, Lin YL, Pasero P. Coquel F, et al. Among authors: techer h. Nature. 2018 May;557(7703):57-61. doi: 10.1038/s41586-018-0050-1. Epub 2018 Apr 18. Nature. 2018. PMID: 29670289
Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments.
Kolinjivadi AM, Sannino V, De Antoni A, Zadorozhny K, Kilkenny M, Técher H, Baldi G, Shen R, Ciccia A, Pellegrini L, Krejci L, Costanzo V. Kolinjivadi AM, et al. Among authors: techer h. Mol Cell. 2017 Sep 7;67(5):867-881.e7. doi: 10.1016/j.molcel.2017.07.001. Epub 2017 Jul 27. Mol Cell. 2017. PMID: 28757209 Free PMC article.
15 results