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The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer's disease.
Ribeiro FC, Cozachenco D, Argyrousi EK, Staniszewski A, Wiebe S, Calixtro JD, Soares-Neto R, Al-Chami A, Sayegh FE, Bermudez S, Arsenault E, Cossenza M, Lacaille JC, Nader K, Sun H, De Felice FG, Lourenco MV, Arancio O, Aguilar-Valles A, Sonenberg N, Ferreira ST. Ribeiro FC, et al. Among authors: aguilar valles a. Alzheimers Dement. 2024 Aug;20(8):5398-5410. doi: 10.1002/alz.14034. Epub 2024 Jun 27. Alzheimers Dement. 2024. PMID: 38934107 Free PMC article.
Beyond the 5-HT2A Receptor: Classic and Nonclassic Targets in Psychedelic Drug Action.
Cameron LP, Benetatos J, Lewis V, Bonniwell EM, Jaster AM, Moliner R, Castrén E, McCorvy JD, Palner M, Aguilar-Valles A. Cameron LP, et al. Among authors: aguilar valles a. J Neurosci. 2023 Nov 8;43(45):7472-7482. doi: 10.1523/JNEUROSCI.1384-23.2023. J Neurosci. 2023. PMID: 37940583 Free PMC article. Review.
A non-hallucinogenic LSD analog with therapeutic potential for mood disorders.
Lewis V, Bonniwell EM, Lanham JK, Ghaffari A, Sheshbaradaran H, Cao AB, Calkins MM, Bautista-Carro MA, Arsenault E, Telfer A, Taghavi-Abkuh FF, Malcolm NJ, El Sayegh F, Abizaid A, Schmid Y, Morton K, Halberstadt AL, Aguilar-Valles A, McCorvy JD. Lewis V, et al. Among authors: aguilar valles a. Cell Rep. 2023 Mar 28;42(3):112203. doi: 10.1016/j.celrep.2023.112203. Epub 2023 Mar 6. Cell Rep. 2023. PMID: 36884348 Free PMC article.
Author Correction: A community-based transcriptomics classification and nomenclature of neocortical cell types.
Yuste R, Hawrylycz M, Aalling N, Aguilar-Valles A, Arendt D, Armañanzas R, Ascoli GA, Bielza C, Bokharaie V, Bergmann TB, Bystron I, Capogna M, Chang Y, Clemens A, de Kock CPJ, DeFelipe J, Dos Santos SE, Dunville K, Feldmeyer D, Fiáth R, Fishell GJ, Foggetti A, Gao X, Ghaderi P, Goriounova NA, Güntürkün O, Hagihara K, Hall VJ, Helmstaedter M, Herculano-Houzel S, Hilscher MM, Hirase H, Hjerling-Leffler J, Hodge R, Huang J, Huda R, Khodosevich K, Kiehn O, Koch H, Kuebler ES, Kühnemund M, Larrañaga P, Lelieveldt B, Louth EL, Lui JH, Mansvelder HD, Marin O, Martinez-Trujillo J, Chameh HM, Mohapatra AN, Munguba H, Nedergaard M, Němec P, Ofer N, Pfisterer UG, Pontes S, Redmond W, Rossier J, Sanes JR, Scheuermann RH, Serrano-Saiz E, Staiger JF, Somogyi P, Tamás G, Tolias AS, Tosches MA, García MT, Wozny C, Wuttke TV, Liu Y, Yuan J, Zeng H, Lein E. Yuste R, et al. Among authors: aguilar valles a. Nat Neurosci. 2021 Apr;24(4):612. doi: 10.1038/s41593-020-00779-0. Nat Neurosci. 2021. PMID: 33742182 Free PMC article. No abstract available.
Lysergic acid diethylamide (LSD) promotes social behavior through mTORC1 in the excitatory neurotransmission.
De Gregorio D, Popic J, Enns JP, Inserra A, Skalecka A, Markopoulos A, Posa L, Lopez-Canul M, He Q, Lafferty CK, Britt JP, Comai S, Aguilar-Valles A, Sonenberg N, Gobbi G. De Gregorio D, et al. Among authors: aguilar valles a. Proc Natl Acad Sci U S A. 2021 Feb 2;118(5):e2020705118. doi: 10.1073/pnas.2020705118. Proc Natl Acad Sci U S A. 2021. PMID: 33495318 Free PMC article.
32 results