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Page 1
Progress on the development of Class A GPCR-biased ligands.
Morales P, Scharf MM, Bermudez M, Egyed A, Franco R, Hansen OK, Jagerovic N, Jakubík J, Keserű GM, Kiss DJ, Kozielewicz P, Larsen O, Majellaro M, Mallo-Abreu A, Navarro G, Prieto-Díaz R, Rosenkilde MM, Sotelo E, Stark H, Werner T, Wingler LM. Morales P, et al. Among authors: majellaro m. Br J Pharmacol. 2024 Sep 11. doi: 10.1111/bph.17301. Online ahead of print. Br J Pharmacol. 2024. PMID: 39261899 Review.
N-Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R).
Intranuovo F, Majellaro M, Mastropasqua F, Delre P, Abatematteo FS, Mangiatordi GF, Stefanachi A, Brea J, Loza MI, Riganti C, Ligresti A, Kumar P, Esposito D, Cristino L, Nicois A, González L, Perrone MG, Colabufo NA, Sotelo E, Abate C, Contino M. Intranuovo F, et al. Among authors: majellaro m. J Med Chem. 2024 Jul 11;67(13):11003-11023. doi: 10.1021/acs.jmedchem.4c00564. Epub 2024 Jun 27. J Med Chem. 2024. PMID: 38937147
Exploring Biginelli-based scaffolds as A2B adenosine receptor antagonists: Unveiling novel structure-activity relationship trends, lead compounds, and potent colorectal anticancer agents.
Prieto-Díaz R, Fojo-Carballo H, Majellaro M, Tandarić T, Azuaje J, Brea J, Loza MI, Barbazán J, Salort G, Chotalia M, Rodríguez-Pampín I, Mallo-Abreu A, Rita Paleo M, García-Mera X, Ciruela F, Gutiérrez-de-Terán H, Sotelo E. Prieto-Díaz R, et al. Among authors: majellaro m. Biomed Pharmacother. 2024 Apr;173:116345. doi: 10.1016/j.biopha.2024.116345. Epub 2024 Mar 5. Biomed Pharmacother. 2024. PMID: 38442670 Free article.
Pharmacological insights emerging from the characterization of a large collection of synthetic cannabinoid receptor agonists designer drugs.
Gioé-Gallo C, Ortigueira S, Brea J, Raïch I, Azuaje J, Paleo MR, Majellaro M, Loza MI, Salas CO, García-Mera X, Navarro G, Sotelo E. Gioé-Gallo C, et al. Among authors: majellaro m. Biomed Pharmacother. 2023 Aug;164:114934. doi: 10.1016/j.biopha.2023.114934. Epub 2023 May 24. Biomed Pharmacother. 2023. PMID: 37236027 Free article.
Development of Fluorescent 4-[4-(3H-Spiro[isobenzofuran-1,4'-piperidin]-1'-yl)butyl]indolyl Derivatives as High-Affinity Probes to Enable the Study of σ Receptors via Fluorescence-Based Techniques.
Abatematteo FS, Majellaro M, Montsch B, Prieto-Díaz R, Niso M, Contino M, Stefanachi A, Riganti C, Mangiatordi GF, Delre P, Heffeter P, Sotelo E, Abate C. Abatematteo FS, et al. Among authors: majellaro m. J Med Chem. 2023 Mar 23;66(6):3798-3817. doi: 10.1021/acs.jmedchem.2c01227. Epub 2023 Mar 15. J Med Chem. 2023. PMID: 36919956 Free PMC article.
N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R).
Graziano G, Delre P, Carofiglio F, Brea J, Ligresti A, Kostrzewa M, Riganti C, Gioè-Gallo C, Majellaro M, Nicolotti O, Colabufo NA, Abate C, Loza MI, Sotelo E, Mangiatordi GF, Contino M, Stefanachi A, Leonetti F. Graziano G, et al. Among authors: majellaro m. Eur J Med Chem. 2023 Feb 15;248:115109. doi: 10.1016/j.ejmech.2023.115109. Epub 2023 Jan 13. Eur J Med Chem. 2023. PMID: 36657299
27 results