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Cytokines drive the formation of memory-like NK cell subsets via epigenetic rewiring and transcriptional regulation.
Foltz JA, Tran J, Wong P, Fan C, Schmidt E, Fisk B, Becker-Hapak M, Russler-Germain DA, Johnson J, Marin ND, Cubitt CC, Pence P, Rueve J, Pureti S, Hwang K, Gao F, Zhou AY, Foster M, Schappe T, Marsala L, Berrien-Elliott MM, Cashen AF, Bednarski JJ, Fertig E, Griffith OL, Griffith M, Wang T, Petti AA, Fehniger TA. Foltz JA, et al. Among authors: schappe t. Sci Immunol. 2024 Jun 28;9(96):eadk4893. doi: 10.1126/sciimmunol.adk4893. Epub 2024 Jun 28. Sci Immunol. 2024. PMID: 38941480
PTEN regulates natural killer cell trafficking in vivo.
Leong JW, Schneider SE, Sullivan RP, Parikh BA, Anthony BA, Singh A, Jewell BA, Schappe T, Wagner JA, Link DC, Yokoyama WM, Fehniger TA. Leong JW, et al. Among authors: schappe t. Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):E700-9. doi: 10.1073/pnas.1413886112. Epub 2015 Feb 2. Proc Natl Acad Sci U S A. 2015. PMID: 25646418 Free PMC article.
MicroRNA-15/16 Antagonizes Myb To Control NK Cell Maturation.
Sullivan RP, Leong JW, Schneider SE, Ireland AR, Berrien-Elliott MM, Singh A, Schappe T, Jewell BA, Sexl V, Fehniger TA. Sullivan RP, et al. Among authors: schappe t. J Immunol. 2015 Sep 15;195(6):2806-17. doi: 10.4049/jimmunol.1500949. Epub 2015 Aug 12. J Immunol. 2015. PMID: 26268657 Free PMC article.
The IL-15-Based ALT-803 Complex Enhances FcγRIIIa-Triggered NK Cell Responses and In Vivo Clearance of B Cell Lymphomas.
Rosario M, Liu B, Kong L, Collins LI, Schneider SE, Chen X, Han K, Jeng EK, Rhode PR, Leong JW, Schappe T, Jewell BA, Keppel CR, Shah K, Hess B, Romee R, Piwnica-Worms DR, Cashen AF, Bartlett NL, Wong HC, Fehniger TA. Rosario M, et al. Among authors: schappe t. Clin Cancer Res. 2016 Feb 1;22(3):596-608. doi: 10.1158/1078-0432.CCR-15-1419. Epub 2015 Sep 30. Clin Cancer Res. 2016. PMID: 26423796 Free PMC article.
Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia.
Romee R, Rosario M, Berrien-Elliott MM, Wagner JA, Jewell BA, Schappe T, Leong JW, Abdel-Latif S, Schneider SE, Willey S, Neal CC, Yu L, Oh ST, Lee YS, Mulder A, Claas F, Cooper MA, Fehniger TA. Romee R, et al. Among authors: schappe t. Sci Transl Med. 2016 Sep 21;8(357):357ra123. doi: 10.1126/scitranslmed.aaf2341. Sci Transl Med. 2016. PMID: 27655849 Free PMC article. Clinical Trial.
CD56bright NK cells exhibit potent antitumor responses following IL-15 priming.
Wagner JA, Rosario M, Romee R, Berrien-Elliott MM, Schneider SE, Leong JW, Sullivan RP, Jewell BA, Becker-Hapak M, Schappe T, Abdel-Latif S, Ireland AR, Jaishankar D, King JA, Vij R, Clement D, Goodridge J, Malmberg KJ, Wong HC, Fehniger TA. Wagner JA, et al. Among authors: schappe t. J Clin Invest. 2017 Nov 1;127(11):4042-4058. doi: 10.1172/JCI90387. Epub 2017 Oct 3. J Clin Invest. 2017. PMID: 28972539 Free PMC article.
MicroRNA-142 Is Critical for the Homeostasis and Function of Type 1 Innate Lymphoid Cells.
Berrien-Elliott MM, Sun Y, Neal C, Ireland A, Trissal MC, Sullivan RP, Wagner JA, Leong JW, Wong P, Mah-Som AY, Wong TN, Schappe T, Keppel CR, Cortez VS, Stamatiades EG, Li MO, Colonna M, Link DC, French AR, Cooper MA, Wang WL, Boldin MP, Reddy P, Fehniger TA. Berrien-Elliott MM, et al. Among authors: schappe t. Immunity. 2019 Sep 17;51(3):479-490.e6. doi: 10.1016/j.immuni.2019.06.016. Epub 2019 Aug 8. Immunity. 2019. PMID: 31402259 Free PMC article.
Stage-Specific Requirement for Eomes in Mature NK Cell Homeostasis and Cytotoxicity.
Wagner JA, Wong P, Schappe T, Berrien-Elliott MM, Cubitt C, Jaeger N, Lee M, Keppel CR, Marin ND, Foltz JA, Marsala L, Neal CC, Sullivan RP, Schneider SE, Keppel MP, Saucier N, Cooper MA, Fehniger TA. Wagner JA, et al. Among authors: schappe t. Cell Rep. 2020 Jun 2;31(9):107720. doi: 10.1016/j.celrep.2020.107720. Cell Rep. 2020. PMID: 32492428 Free PMC article.
39 results