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206 results

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Page 1
The FBXO45-GEF-H1 axis controls germinal center formation and B-cell lymphomagenesis.
Sahasrabuddhe AA, Chen X, Ma K, Wu R, Liang HC, Kapoor R, Chhipa RR, Onder O, McFetridge C, Van Arnam JS, Zhang X, Morrissette JJD, Pillai V, Li MM, Szankasi P, Basrur V, Conlon KP, Raabe TD, Bailey NG, Hogaboam CM, Rottapel R, Kim J, López C, Schlesner M, Siebert R, Dreval K, Morin RD, Moro L, Pagano M, Staudt LM, Lim MS, Elenitoba-Johnson KSJ. Sahasrabuddhe AA, et al. Among authors: schlesner m. Cancer Discov. 2025 Jan 17. doi: 10.1158/2159-8290.CD-24-0442. Online ahead of print. Cancer Discov. 2025. PMID: 39820335
Navigating Illumina DNA methylation data: biology versus technical artefacts.
Glaser S, Kretzmer H, Kolassa IT, Schlesner M, Fischer A, Fenske I, Siebert R, Ammerpohl O. Glaser S, et al. Among authors: schlesner m. NAR Genom Bioinform. 2024 Dec 18;6(4):lqae181. doi: 10.1093/nargab/lqae181. eCollection 2024 Dec. NAR Genom Bioinform. 2024. PMID: 39703427 Free PMC article.
The chromosomal translocation t(1;6)(p35.3;p25.2), recurrent in chronic lymphocytic leukaemia, leads to RCC1::IRF4 fusion.
Jayne S, López C, Put N, Nagel I, Lierman E, Penas EMM, Michaux L, Ahearne MJ, Walter HS, Bens S, Drewes C, Szczepanowski M, Schlesner M, Rosenstiel P, Wlodarska I, Siebert R, Dyer MJS. Jayne S, et al. Among authors: schlesner m. Br J Haematol. 2024 Dec;205(6):2321-2326. doi: 10.1111/bjh.19790. Epub 2024 Oct 15. Br J Haematol. 2024. PMID: 39406248 Free PMC article.
Clinical and Molecular Risk Factors in Extracranial Malignant Rhabdoid Tumors: Toward an Integrated Model of High-Risk Tumors.
Fincke VE, Steinbügl M, Chun HE, Nemes K, Mucha M, Loßner M, Dorn F, Gastberger K, Bühner S, Sill M, Kröncke T, Siebert R, Melchior P, Furtwängler R, Schlesner M, Vokuhl C, Röcken C, Johann PD, Frühwald MC. Fincke VE, et al. Among authors: schlesner m. Clin Cancer Res. 2024 Oct 15;30(20):4667-4680. doi: 10.1158/1078-0432.CCR-23-3489. Clin Cancer Res. 2024. PMID: 39120581
Whole-exome sequencing reveals novel cancer genes and actionable targets in biliary tract cancers in primary sclerosing cholangitis.
Grimsrud MM, Forster M, Goeppert B, Hemmrich-Stanisak G, Sax I, Grzyb K, Braadland PR, Charbel A, Metzger C, Albrecht T, Steiert TA, Schlesner M, Manns MP, Vogel A, Yaqub S, Karlsen TH, Schirmacher P, Boberg KM, Franke A, Roessler S, Folseraas T. Grimsrud MM, et al. Among authors: schlesner m. Hepatol Commun. 2024 Jul 5;8(7):e0461. doi: 10.1097/HC9.0000000000000461. eCollection 2024 Jul 1. Hepatol Commun. 2024. PMID: 38967597 Free PMC article.
Synergy of retinoic acid and BH3 mimetics in MYC(N)-driven embryonal nervous system tumours.
Seiboldt T, Zeiser C, Nguyen D, Celikyürekli S, Herter S, Najafi S, Stroh-Dege A, Meulenbroeks C, Mack N, Salem-Altintas R, Westermann F, Schlesner M, Milde T, Kool M, Holland-Letz T, Vogler M, Peterziel H, Witt O, Oehme I. Seiboldt T, et al. Among authors: schlesner m. Br J Cancer. 2024 Sep;131(4):763-777. doi: 10.1038/s41416-024-02740-5. Epub 2024 Jun 28. Br J Cancer. 2024. PMID: 38942989 Free PMC article.
Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction.
Salcedo A, Tarabichi M, Buchanan A, Espiritu SMG, Zhang H, Zhu K, Ou Yang TH, Leshchiner I, Anastassiou D, Guan Y, Jang GH, Mootor MFE, Haase K, Deshwar AG, Zou W, Umar I, Dentro S, Wintersinger JA, Chiotti K, Demeulemeester J, Jolly C, Sycza L, Ko M; PCAWG Evolution and Heterogeneity Working Group; SMC-Het Participants; Wedge DC, Morris QD, Ellrott K, Van Loo P, Boutros PC. Salcedo A, et al. Nat Biotechnol. 2024 Jun 11. doi: 10.1038/s41587-024-02250-y. Online ahead of print. Nat Biotechnol. 2024. PMID: 38862616
A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1.
Hai L, Hoffmann DC, Wagener RJ, Azorin DD, Hausmann D, Xie R, Huppertz MC, Hiblot J, Sievers P, Heuer S, Ito J, Cebulla G, Kourtesakis A, Kaulen LD, Ratliff M, Mandelbaum H, Jung E, Jabali A, Horschitz S, Ernst KJ, Reibold D, Warnken U, Venkataramani V, Will R, Suvà ML, Herold-Mende C, Sahm F, Winkler F, Schlesner M, Wick W, Kessler T. Hai L, et al. Among authors: schlesner m. Nat Commun. 2024 Feb 6;15(1):968. doi: 10.1038/s41467-024-45067-8. Nat Commun. 2024. PMID: 38320988 Free PMC article.
PerSurge (NOA-30) phase II trial of perampanel treatment around surgery in patients with progressive glioblastoma.
Heuer S, Burghaus I, Gose M, Kessler T, Sahm F, Vollmuth P, Venkataramani V, Hoffmann D, Schlesner M, Ratliff M, Hopf C, Herrlinger U, Ricklefs F, Bendszus M, Krieg SM, Wick A, Wick W, Winkler F. Heuer S, et al. Among authors: schlesner m. BMC Cancer. 2024 Jan 26;24(1):135. doi: 10.1186/s12885-024-11846-1. BMC Cancer. 2024. PMID: 38279087 Free PMC article. Clinical Trial.
206 results