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IRF4 impedes human CD8 T cell function and promotes cell proliferation and PD-1 expression.
Hirsch T, Neyens D, Duhamel C, Bayard A, Vanhaver C, Luyckx M, Sala de Oyanguren F, Wildmann C, Dauguet N, Squifflet JL, Montiel V, Deschamps M, van der Bruggen P. Hirsch T, et al. Among authors: squifflet jl. Cell Rep. 2024 Jul 23;43(7):114401. doi: 10.1016/j.celrep.2024.114401. Epub 2024 Jun 27. Cell Rep. 2024. PMID: 38943641 Free article.
A galectin-3 ligand corrects the impaired function of human CD4 and CD8 tumor-infiltrating lymphocytes and favors tumor rejection in mice.
Demotte N, Wieërs G, Van Der Smissen P, Moser M, Schmidt C, Thielemans K, Squifflet JL, Weynand B, Carrasco J, Lurquin C, Courtoy PJ, van der Bruggen P. Demotte N, et al. Among authors: squifflet jl. Cancer Res. 2010 Oct 1;70(19):7476-88. doi: 10.1158/0008-5472.CAN-10-0761. Epub 2010 Aug 18. Cancer Res. 2010. PMID: 20719885 Free article.
A short treatment with galactomannan GM-CT-01 corrects the functions of freshly isolated human tumor-infiltrating lymphocytes.
Demotte N, Bigirimana R, Wieërs G, Stroobant V, Squifflet JL, Carrasco J, Thielemans K, Baurain JF, Van Der Smissen P, Courtoy PJ, van der Bruggen P. Demotte N, et al. Among authors: squifflet jl. Clin Cancer Res. 2014 Apr 1;20(7):1823-33. doi: 10.1158/1078-0432.CCR-13-2459. Epub 2014 Feb 13. Clin Cancer Res. 2014. PMID: 24526733
24 results