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367 results

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Therapeutic potential of hydantoin and thiohydantoin compounds against Schistosoma mansoni: An integrated in vitro, DNA, ultrastructural, and ADMET in silico approach.
Almeida Júnior AS, Freitas Viana Leal MM, Marques DSC, Silva ALD, Souza Bezerra R, Siqueira de Souza YF, Mendonça Silveira ME, Santos FA, Alves LC, de Lima Aires A, Cruz Filho IJD, do Carmo Alves de Lima M. Almeida Júnior AS, et al. Among authors: alves lc. Mol Biochem Parasitol. 2024 Dec;260:111646. doi: 10.1016/j.molbiopara.2024.111646. Epub 2024 Jun 29. Mol Biochem Parasitol. 2024. PMID: 38950658
Synthesis, cytotoxicity and antifungal activity of 5-nitro-thiophene-thiosemicarbazones derivatives.
de Araújo Neto LN, do Carmo Alves de Lima M, de Oliveira JF, de Souza ER, Buonafina MDS, Vitor Anjos MN, Brayner FA, Alves LC, Neves RP, Mendonça-Junior FJB. de Araújo Neto LN, et al. Among authors: alves lc. Chem Biol Interact. 2017 Jun 25;272:172-181. doi: 10.1016/j.cbi.2017.05.005. Epub 2017 May 4. Chem Biol Interact. 2017. PMID: 28479098 Free article.
Phthalimido-thiazole as privileged scaffold: activity against immature and adult worms of Schistosoma mansoni.
de Oliveira SA, de Oliveira Barbosa M, Filho CALM, Oliveira AR, de Sousa FA, de Farias Santiago E, de Oliveira Filho GB, de Moraes Gomes PAT, da Conceição JM, Brayner FA, Alves LC, Leite ACL. de Oliveira SA, et al. Among authors: alves lc. Parasitol Res. 2018 Jul;117(7):2105-2115. doi: 10.1007/s00436-018-5897-4. Epub 2018 May 7. Parasitol Res. 2018. PMID: 29736731
In vitro activity, ultrastructural studies and in silico pharmacokinetic properties of indol-3-yl-thiosemicarbazones derivatives and analogues against juvenile and adult worms of S. mansoni.
de Almeida Júnior ASA, de Oliveira JF, da Silva AL, da Rocha RET, Junior NCP, Gouveia ALA, da Silva RMF, de Azevedo Albuquerque MCP, Brayner FA, Alves LC, do Carmo Alves de Lima M. de Almeida Júnior ASA, et al. Among authors: alves lc. Eur J Pharm Sci. 2019 Oct 1;138:104985. doi: 10.1016/j.ejps.2019.104985. Epub 2019 Jul 5. Eur J Pharm Sci. 2019. PMID: 31283945
Lignin from Morinda citrifolia leaves: Physical and chemical characterization, in vitro evaluation of antioxidant, cytotoxic, antiparasitic and ultrastructural activities.
da Silva PR, do Carmo Alves de Lima M, Souza TP, Sandes JM, da Conceição Alves de Lima A, Neto PJR, Dos Santos FAB, Alves LC, da Silva RMF, de Moraes Rocha GJ, da Cruz Filho IJ. da Silva PR, et al. Among authors: alves lc. Int J Biol Macromol. 2021 Dec 15;193(Pt B):1799-1812. doi: 10.1016/j.ijbiomac.2021.11.013. Epub 2021 Nov 12. Int J Biol Macromol. 2021. PMID: 34774863
Synthesis, in vitro schistosomicidal activity and ultrastructural alterations caused by thiosemicarbazones and thiazolidinones against juvenile and adult Schistosoma mansoni worms (Sambon, 1907).
Tavares da Rocha RE, de Almeida Júnior ASA, Júnior NCP, do Nascimento AV, Leite NMS, de Oliveira JF, Alves de Lima MDC, Feitosa APS, Bezerra de Mélo ME, Brayner FA, Alves LC. Tavares da Rocha RE, et al. Among authors: alves de lima mdc, alves lc. Mol Biochem Parasitol. 2022 Nov;252:111520. doi: 10.1016/j.molbiopara.2022.111520. Epub 2022 Sep 16. Mol Biochem Parasitol. 2022. PMID: 36122704 Free article.
In vitro evaluation of alkaline lignins as antiparasitic agents and their use as an excipient in the release of benznidazole.
da Cruz Filho IJ, Duarte DMFA, da Conceição Alves de Lima D, Marques DSC, Dos Santos FAB, Alves LC, de Lima Aires A, Nogueira F, do Carmo Alves de Lima M. da Cruz Filho IJ, et al. Among authors: alves lc. Int J Biol Macromol. 2023 Mar 15;231:123339. doi: 10.1016/j.ijbiomac.2023.123339. Epub 2023 Jan 20. Int J Biol Macromol. 2023. PMID: 36682648
367 results