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Response eQTLs, chromatin accessibility, and 3D chromatin structure in chondrocytes provide mechanistic insight into osteoarthritis risk.
Kramer NE, Byun S, Coryell P, D'Costa S, Thulson E, Kim H, Parkus SM, Bond ML, Klein ER, Shine J, Chubinskaya S, Love MI, Mohlke KL, Diekman BO, Loeser RF, Phanstiel DH. Kramer NE, et al. Among authors: diekman bo. bioRxiv [Preprint]. 2024 Oct 31:2024.05.05.592567. doi: 10.1101/2024.05.05.592567. bioRxiv. 2024. PMID: 38952796 Free PMC article. Preprint.
SIRT6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes.
Copp ME, Shine J, Brown HL, Nimmala KR, Chubinskaya S, Collins JA, Loeser RF, Diekman BO. Copp ME, et al. Among authors: diekman bo. bioRxiv [Preprint]. 2023 Feb 28:2023.02.27.530205. doi: 10.1101/2023.02.27.530205. bioRxiv. 2023. Update in: Aging (Albany NY). 2023 Dec 9;15(23):13628-13645. doi: 10.18632/aging.205394 PMID: 36909504 Free PMC article. Updated. Preprint.
Ageing and the pathogenesis of osteoarthritis.
Loeser RF, Collins JA, Diekman BO. Loeser RF, et al. Among authors: diekman bo. Nat Rev Rheumatol. 2016 Jul;12(7):412-20. doi: 10.1038/nrrheum.2016.65. Epub 2016 May 19. Nat Rev Rheumatol. 2016. PMID: 27192932 Free PMC article. Review.
Targeting aging for disease modification in osteoarthritis.
Collins JA, Diekman BO, Loeser RF. Collins JA, et al. Among authors: diekman bo. Curr Opin Rheumatol. 2018 Jan;30(1):101-107. doi: 10.1097/BOR.0000000000000456. Curr Opin Rheumatol. 2018. PMID: 28957964 Free PMC article. Review.
46 results