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A chemogenetic approach for dopamine imaging with tunable sensitivity.
Labouesse MA, Wilhelm M, Kagiampaki Z, Yee AG, Denis R, Harada M, Gresch A, Marinescu AM, Otomo K, Curreli S, Serratosa Capdevila L, Zhou X, Cola RB, Ravotto L, Glück C, Cherepanov S, Weber B, Zhou X, Katner J, Svensson KA, Fellin T, Trudeau LE, Ford CP, Sych Y, Patriarchi T. Labouesse MA, et al. Among authors: svensson ka. Nat Commun. 2024 Jul 2;15(1):5551. doi: 10.1038/s41467-024-49442-3. Nat Commun. 2024. PMID: 38956067 Free PMC article.
Effects of DPTQ, a novel positive allosteric modulator of the dopamine D1 receptor, on spontaneous eye blink rate and spatial working memory in the nonhuman primate.
Castner SA, Zhang L, Yang CR, Hao J, Cramer JW, Wang X, Bruns RF, Marston H, Svensson KA, Williams GV. Castner SA, et al. Among authors: svensson ka. Psychopharmacology (Berl). 2023 May;240(5):1033-1048. doi: 10.1007/s00213-022-06282-7. Epub 2023 Mar 24. Psychopharmacology (Berl). 2023. PMID: 36961560 Free PMC article.
Synthesis and Preclinical Characterization of LY3154885, a Human Dopamine D1 Receptor Positive Allosteric Modulator with an Improved Nonclinical Drug-Drug Interaction Risk Profile.
Hao J, Beck J, Zhou X, Lackner GL, Johnston R, Reinhard M, Goldsmith P, Hollinshead S, Dehlinger V, Filla SA, Wang XS, Richardson J, Posada M, Mohutsky M, Schober D, Katner JS, Chen Q, Hu B, Remick DM, Coates DA, Mathes BM, Hawk MK, Svensson KA, Hembre E. Hao J, et al. Among authors: svensson ka. J Med Chem. 2022 Mar 10;65(5):3786-3797. doi: 10.1021/acs.jmedchem.1c01887. Epub 2022 Feb 17. J Med Chem. 2022. PMID: 35175768
62 results