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Discovery of Potent and Orally Bioavailable Pyrimidine Amide cGAS Inhibitors via Structure-Guided Hybridization.
Cyr P, Fader LD, Burch JD, Pike KA, Sietsema DV, Boily MO, Ciblat S, Sgarioto N, Skeldon AM, Gaudreault S, Le Gros P, Dumais V, McKay DJJ, Abraham NS, Seliniotakis R, Beveridge RE. Cyr P, et al. Among authors: beveridge re. ACS Med Chem Lett. 2024 Nov 25;15(12):2201-2209. doi: 10.1021/acsmedchemlett.4c00471. eCollection 2024 Dec 12. ACS Med Chem Lett. 2024. PMID: 39691514
Lentiviral vector packaging and producer cell lines yield titers equivalent to the industry-standard four-plasmid process.
Tridgett M, Mulet M, Johny SP, Ababi M, Raghunath M, Fustinoni C, Galabova B, Fernández-Díaz C, Mikalajūnaitė I, Tomás HA, Kucej M, Dunajová L, Zgrundo Z, Page E, McCall L, Parker-Manuel R, Payne T, Peckett M, Kent J, Holland L, Asatryan R, Montgomery L, Chow TL, Beveridge R, Salkauskaite I, Alam MT, Hollard D, Dowding S, Gabriel HB, Branciaroli C, Cawood R, Valenti W, Chang D, Patrício MI, Liu Q. Tridgett M, et al. Among authors: beveridge r. Mol Ther Methods Clin Dev. 2024 Aug 8;32(3):101315. doi: 10.1016/j.omtm.2024.101315. eCollection 2024 Sep 12. Mol Ther Methods Clin Dev. 2024. PMID: 39282073 Free PMC article.
Spatial distribution of tumour immune infiltrate predicts outcomes of patients with high-risk soft tissue sarcomas after neoadjuvant chemotherapy.
Pasquali S, Vallacchi V, Lalli L, Collini P, Barisella M, Romagosa C, Bague S, Coindre JM, Dei Tos AP, Palmerini E, Quagliuolo V, Martin-Broto J, Lopez-Pousa A, Grignani G, Blay JY, Beveridge RD, Casiraghi E, Brich S, Renne SL, Bergamaschi L, Vergani B, Sbaraglia M, Casali PG, Rivoltini L, Stacchiotti S, Gronchi A. Pasquali S, et al. Among authors: beveridge rd. EBioMedicine. 2024 Aug;106:105220. doi: 10.1016/j.ebiom.2024.105220. Epub 2024 Jul 16. EBioMedicine. 2024. PMID: 39018755 Free PMC article. Clinical Trial.
Strathclyde minor groove binders (S-MGBs) with activity against Acanthamoeba castellanii.
Mcgee LMC, Carpinteyro Sanchez AG, Perieteanu M, Eskandari K, Bian Y, Mackie L, Young L, Beveridge R, Suckling CJ, Roberts CW, Scott FJ. Mcgee LMC, et al. Among authors: beveridge r. J Antimicrob Chemother. 2024 Sep 3;79(9):2251-2258. doi: 10.1093/jac/dkae221. J Antimicrob Chemother. 2024. PMID: 38980760 Free PMC article.
206 results