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Assessing the kinetics of oxygen-unloading from red cells using FlowScore, a flow-cytometric proxy of the functional quality of blood.
Rabcuka J, Smethurst PA, Dammert K, Saker J, Aran G, Walsh GM, Tan JCG, Codinach M, McTaggart K, Marks DC, Bakker SJL, McMahon A, Di Angelantonio E, Roberts DJ, Blonski S, Korczyk PM, Shirakami A, Cardigan R, Swietach P. Rabcuka J, et al. Among authors: swietach p. EBioMedicine. 2024 Dec 13;111:105498. doi: 10.1016/j.ebiom.2024.105498. Online ahead of print. EBioMedicine. 2024. PMID: 39674089 Free PMC article.
The release of GLP-1 from gut L cells is inhibited by low extracellular pH.
Garbutt P, Cyranka M, Michl J, Maejima Y, Vedovato N, Shimomura K, Swietach P, de Wet H. Garbutt P, et al. Among authors: swietach p. Obesity (Silver Spring). 2024 Oct;32(10):1819-1824. doi: 10.1002/oby.24125. Epub 2024 Sep 5. Obesity (Silver Spring). 2024. PMID: 39238194 Free PMC article.
Innovating cancer drug discovery with refined phenotypic screens.
Wang Z, Hulikova A, Swietach P. Wang Z, et al. Among authors: swietach p. Trends Pharmacol Sci. 2024 Aug;45(8):723-738. doi: 10.1016/j.tips.2024.06.001. Epub 2024 Jul 15. Trends Pharmacol Sci. 2024. PMID: 39013672 Free article. Review.
Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation.
Park KC, Crump NT, Louwman N, Krywawych S, Cheong YJ, Vendrell I, Gill EK, Gunadasa-Rohling M, Ford KL, Hauton D, Fournier M, Pires E, Watson L, Roseman G, Holder J, Koschinski A, Carnicer R, Curtis MK, Zaccolo M, Hulikova A, Fischer R, Kramer HB, McCullagh JSO, Trefely S, Milne TA, Swietach P. Park KC, et al. Among authors: swietach p. Nat Cardiovasc Res. 2023 Dec;2(12):1221-1245. doi: 10.1038/s44161-023-00365-0. Epub 2023 Nov 23. Nat Cardiovasc Res. 2023. PMID: 38500966 Free PMC article.
107 results