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PI3Kγ inhibition circumvents inflammation and vascular leak in SARS-CoV-2 and other infections.
Shepard RM, Ghebremedhin A, Pratumchai I, Robinson SR, Betts C, Hu J, Sasik R, Fisch KM, Zak J, Chen H, Paradise M, Rivera J, Amjad M, Uchiyama S, Seo H, Campos AD, Dayao DA, Tzipori S, Piedra-Mora C, Das S, Hasteh F, Russo H, Sun X, Xu L, E Alexander LC, Duran JM, Odish M, Pretorius V, Kirchberger NC, Chin SM, Von Schalscha T, Cheresh D, Morrey JD, Alargova R, O'Connell B, Martinot TA, Patel SP, Nizet V, Martinot AJ, Coussens LM, Teijaro JR, Varner JA. Shepard RM, et al. Among authors: paradise m. Sci Transl Med. 2024 Jul 3;16(754):eadi6887. doi: 10.1126/scitranslmed.adi6887. Epub 2024 Jul 3. Sci Transl Med. 2024. PMID: 38959328 Free PMC article.
Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease.
Duperron MG, Knol MJ, Le Grand Q, Evans TE, Mishra A, Tsuchida A, Roshchupkin G, Konuma T, Trégouët DA, Romero JR, Frenzel S, Luciano M, Hofer E, Bourgey M, Dueker ND, Delgado P, Hilal S, Tankard RM, Dubost F, Shin J, Saba Y, Armstrong NJ, Bordes C, Bastin ME, Beiser A, Brodaty H, Bülow R, Carrera C, Chen C, Cheng CY, Deary IJ, Gampawar PG, Himali JJ, Jiang J, Kawaguchi T, Li S, Macalli M, Marquis P, Morris Z, Muñoz Maniega S, Miyamoto S, Okawa M, Paradise M, Parva P, Rundek T, Sargurupremraj M, Schilling S, Setoh K, Soukarieh O, Tabara Y, Teumer A, Thalamuthu A, Trollor JN, Valdés Hernández MC, Vernooij MW, Völker U, Wittfeld K, Wong TY, Wright MJ, Zhang J, Zhao W, Zhu YC, Schmidt H, Sachdev PS, Wen W, Yoshida K, Joutel A, Satizabal CL, Sacco RL, Bourque G; CHARGE consortium; Lathrop M, Paus T, Fernandez-Cadenas I, Yang Q, Mazoyer B, Boutinaud P, Okada Y, Grabe HJ, Mather KA, Schmidt R, Joliot M, Ikram MA, Matsuda F, Tzourio C, Wardlaw JM, Seshadri S, Adams HHH, Debette S. Duperron MG, et al. Among authors: paradise m. Nat Med. 2023 Apr;29(4):950-962. doi: 10.1038/s41591-023-02268-w. Epub 2023 Apr 17. Nat Med. 2023. PMID: 37069360 Free PMC article.
Plasma lipidomic biomarker analysis reveals distinct lipid changes in vascular dementia.
Liu Y, Chan DKY, Thalamuthu A, Wen W, Jiang J, Paradise M, Lee T, Crawford J, Wai Kin Wong M, Hua Xu Y, Poljak A, Pickford R, Sachdev PS, Braidy N. Liu Y, et al. Among authors: paradise m. Comput Struct Biotechnol J. 2020 Jun 9;18:1613-1624. doi: 10.1016/j.csbj.2020.06.001. eCollection 2020. Comput Struct Biotechnol J. 2020. PMID: 32670502 Free PMC article.
Vascular Cognitive Disorder.
Paradise MB, Sachdev PS. Paradise MB, et al. Semin Neurol. 2019 Apr;39(2):241-250. doi: 10.1055/s-0039-1678582. Epub 2019 Mar 29. Semin Neurol. 2019. PMID: 30925616 Review.
45 results