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PI3Kγ inhibition circumvents inflammation and vascular leak in SARS-CoV-2 and other infections.
Shepard RM, Ghebremedhin A, Pratumchai I, Robinson SR, Betts C, Hu J, Sasik R, Fisch KM, Zak J, Chen H, Paradise M, Rivera J, Amjad M, Uchiyama S, Seo H, Campos AD, Dayao DA, Tzipori S, Piedra-Mora C, Das S, Hasteh F, Russo H, Sun X, Xu L, E Alexander LC, Duran JM, Odish M, Pretorius V, Kirchberger NC, Chin SM, Von Schalscha T, Cheresh D, Morrey JD, Alargova R, O'Connell B, Martinot TA, Patel SP, Nizet V, Martinot AJ, Coussens LM, Teijaro JR, Varner JA. Shepard RM, et al. Among authors: piedra mora c. Sci Transl Med. 2024 Jul 3;16(754):eadi6887. doi: 10.1126/scitranslmed.adi6887. Epub 2024 Jul 3. Sci Transl Med. 2024. PMID: 38959328 Free PMC article.
Cathepsin W, T-cell receptor-associated transmembrane adapter 1, lymphotactin and killer cell lectin like receptor K1 are sensitive and specific RNA biomarkers of canine epitheliotropic lymphoma.
Olayinka JT, Nagarkar A, Ma DJ, Wong NB, Romasco A, Piedra-Mora C, Wrijil L, David CN, Gardner HL, Robinson NA, Hughes KL, Barton B, London CA, Almela RM, Richmond JM. Olayinka JT, et al. Among authors: piedra mora c. Front Vet Sci. 2023 Nov 3;10:1225764. doi: 10.3389/fvets.2023.1225764. eCollection 2023. Front Vet Sci. 2023. PMID: 38026637 Free PMC article.
Reduced SARS-CoV-2 disease outcomes in Syrian hamsters receiving immune sera: Quantitative image analysis in pathologic assessments.
Piedra-Mora C, Robinson SR, Tostanoski LH, Dayao DAE, Chandrashekar A, Bauer K, Wrijil L, Ducat S, Hayes T, Yu J, Bondzie EA, McMahan K, Sellers D, Giffin V, Hope D, Nampanya F, Mercado NB, Kar S, Andersen H, Tzipori S, Barouch DH, Martinot AJ. Piedra-Mora C, et al. Vet Pathol. 2022 Jul;59(4):648-660. doi: 10.1177/03009858221095794. Epub 2022 May 6. Vet Pathol. 2022. PMID: 35521761
Ad26.COV2.S prevents upregulation of SARS-CoV-2 induced pathways of inflammation and thrombosis in hamsters and rhesus macaques.
Aid M, Vidal SJ, Piedra-Mora C, Ducat S, Chan CN, Bondoc S, Colarusso A, Starke CE, Nekorchuk M, Busman-Sahay K, Estes JD, Martinot AJ, Barouch DH. Aid M, et al. Among authors: piedra mora c. PLoS Pathog. 2022 Apr 8;18(4):e1009990. doi: 10.1371/journal.ppat.1009990. eCollection 2022 Apr. PLoS Pathog. 2022. PMID: 35395058 Free PMC article.
Reduced pathogenicity of the SARS-CoV-2 omicron variant in hamsters.
McMahan K, Giffin V, Tostanoski LH, Chung B, Siamatu M, Suthar MS, Halfmann P, Kawaoka Y, Piedra-Mora C, Jain N, Ducat S, Kar S, Andersen H, Lewis MG, Martinot AJ, Barouch DH. McMahan K, et al. Among authors: piedra mora c. Med. 2022 Apr 8;3(4):262-268.e4. doi: 10.1016/j.medj.2022.03.004. Epub 2022 Mar 17. Med. 2022. PMID: 35313451 Free PMC article.
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