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Page 1
PI3Kγ inhibition circumvents inflammation and vascular leak in SARS-CoV-2 and other infections.
Shepard RM, Ghebremedhin A, Pratumchai I, Robinson SR, Betts C, Hu J, Sasik R, Fisch KM, Zak J, Chen H, Paradise M, Rivera J, Amjad M, Uchiyama S, Seo H, Campos AD, Dayao DA, Tzipori S, Piedra-Mora C, Das S, Hasteh F, Russo H, Sun X, Xu L, Crotty Alexander LE, Duran JM, Odish M, Pretorius V, Kirchberger NC, Chin SM, Von Schalscha T, Cheresh D, Morrey JD, Alargova R, O'Connell B, Martinot TA, Patel SP, Nizet V, Martinot AJ, Coussens LM, Teijaro JR, Varner JA. Shepard RM, et al. Among authors: pratumchai i. Sci Transl Med. 2024 Jul 3;16(754):eadi6887. doi: 10.1126/scitranslmed.adi6887. Epub 2024 Jul 3. Sci Transl Med. 2024. PMID: 38959328 Free PMC article.
JAK inhibition enhances checkpoint blockade immunotherapy in patients with Hodgkin lymphoma.
Zak J, Pratumchai I, Marro BS, Marquardt KL, Zavareh RB, Lairson LL, Oldstone MBA, Varner JA, Hegerova L, Cao Q, Farooq U, Kenkre VP, Bachanova V, Teijaro JR. Zak J, et al. Among authors: pratumchai i. Science. 2024 Jun 21;384(6702):eade8520. doi: 10.1126/science.ade8520. Epub 2024 Jun 21. Science. 2024. PMID: 38900864 Free PMC article. Clinical Trial.
Transient EZH2 suppression by Tazemetostat during in vitro expansion maintains T cell stemness and improves adoptive T cell therapy.
Hou Y, Zak J, Shi Y, Pratumchai I, Dinner B, Wang W, Qin K, Weber E, Teijaro JR, Wu P. Hou Y, et al. Among authors: pratumchai i. bioRxiv [Preprint]. 2023 Feb 7:2023.02.07.527459. doi: 10.1101/2023.02.07.527459. bioRxiv. 2023. Update in: Cancer Immunol Res. 2025 Jan 9;13(1):47-65. doi: 10.1158/2326-6066.CIR-24-0089 PMID: 36798389 Free PMC article. Updated. Preprint.
B cell-derived IL-27 promotes control of persistent LCMV infection.
Pratumchai I, Zak J, Huang Z, Min B, Oldstone MBA, Teijaro JR. Pratumchai I, et al. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2116741119. doi: 10.1073/pnas.2116741119. Proc Natl Acad Sci U S A. 2022. PMID: 35022243 Free PMC article.