Jacobson KA - Search Results

1

Lipid Trolling to Optimize A₃ Adenosine Receptor-Positive Allosteric Modulators (PAMs).

Pradhan B, Pavan M, Fisher CL, Salmaso V, Wan TC, Keyes RF, Rollison N, Suresh RR, Kumar TS, Gao ZG, Smith BC, Auchampach JA, Jacobson KA. Pradhan B, et al. Among authors: jacobson ka. J Med Chem. 2024 Jul 25;67(14):12221-12247. doi: 10.1021/acs.jmedchem.4c00944. Epub 2024 Jul 3. J Med Chem. 2024. PMID: 38959401

2

Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.

Jacobson KA, van Galen PJ, Williams M. Jacobson KA, et al. J Med Chem. 1992 Feb 7;35(3):407-22. doi: 10.1021/jm00081a001. J Med Chem. 1992. PMID: 1738138 Free PMC article. Review. No abstract available.

3

Functionalized congener approach to muscarinic antagonists: analogues of pirenzepine.

Karton Y, Bradbury BJ, Baumgold J, Paek R, Jacobson KA. Karton Y, et al. Among authors: jacobson ka. J Med Chem. 1991 Jul;34(7):2133-45. doi: 10.1021/jm00111a032. J Med Chem. 1991. PMID: 2066986 Free PMC article.

4

Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors.

Siddiqi SM, Jacobson KA, Esker JL, Olah ME, Ji XD, Melman N, Tiwari KN, Secrist JA 3rd, Schneller SW, Cristalli G, et al. Siddiqi SM, et al. Among authors: jacobson ka. J Med Chem. 1995 Mar 31;38(7):1174-88. doi: 10.1021/jm00007a014. J Med Chem. 1995. PMID: 7707320 Free PMC article.

5

Structure-activity relationships of 9-alkyladenine and ribose-modified adenosine derivatives at rat A3 adenosine receptors.

Jacobson KA, Siddiqi SM, Olah ME, Ji XD, Melman N, Bellamkonda K, Meshulam Y, Stiles GL, Kim HO. Jacobson KA, et al. J Med Chem. 1995 May 12;38(10):1720-35. doi: 10.1021/jm00010a017. J Med Chem. 1995. PMID: 7752196 Free PMC article.

6

Structure-activity relationships of 1,3-dialkylxanthine derivatives at rat A3 adenosine receptors.

Kim HO, Ji XD, Melman N, Olah ME, Stiles GL, Jacobson KA. Kim HO, et al. Among authors: jacobson ka. J Med Chem. 1994 Sep 30;37(20):3373-82. doi: 10.1021/jm00046a022. J Med Chem. 1994. PMID: 7932565 Free PMC article.

7

2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors.

Kim HO, Ji XD, Siddiqi SM, Olah ME, Stiles GL, Jacobson KA. Kim HO, et al. Among authors: jacobson ka. J Med Chem. 1994 Oct 14;37(21):3614-21. doi: 10.1021/jm00047a018. J Med Chem. 1994. PMID: 7932588 Free PMC article.

8

Selective ligands for rat A3 adenosine receptors: structure-activity relationships of 1,3-dialkylxanthine 7-riboside derivatives.

Kim HO, Ji XD, Melman N, Olah ME, Stiles GL, Jacobson KA. Kim HO, et al. Among authors: jacobson ka. J Med Chem. 1994 Nov 11;37(23):4020-30. doi: 10.1021/jm00049a021. J Med Chem. 1994. PMID: 7966162 Free PMC article.

9

Identification of potent, selective P2Y-purinoceptor agonists: structure-activity relationships for 2-thioether derivatives of adenosine 5'-triphosphate.

Fischer B, Boyer JL, Hoyle CH, Ziganshin AU, Brizzolara AL, Knight GE, Zimmet J, Burnstock G, Harden TK, Jacobson KA. Fischer B, et al. Among authors: jacobson ka. J Med Chem. 1993 Nov 26;36(24):3937-46. doi: 10.1021/jm00076a023. J Med Chem. 1993. PMID: 8254622 Free PMC article.

10

Structure-activity relationships of 8-styrylxanthines as A2-selective adenosine antagonists.

Jacobson KA, Gallo-Rodriguez C, Melman N, Fischer B, Maillard M, van Bergen A, van Galen PJ, Karton Y. Jacobson KA, et al. J Med Chem. 1993 May 14;36(10):1333-42. doi: 10.1021/jm00062a005. J Med Chem. 1993. PMID: 8496902 Free PMC article.

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