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A "Prime and Expand" strategy using the multifunctional fusion proteins to generate memory-like NK cells for cell therapy.
Shrestha N, Dee MJ, Chaturvedi P, Leclerc GM, Mathyer M, Dufour C, Arthur L, Becker-Hapak M, Foster M, McClain E, Pena NV, Kage K, Zhu X, George V, Liu B, Egan J, Echeverri C, Wang M, You L, Kong L, Li L, Berrien-Elliott MM, Cooper ML, Fehniger TA, Rhode PR, Wong HC. Shrestha N, et al. Among authors: li l. Cancer Immunol Immunother. 2024 Jul 3;73(9):179. doi: 10.1007/s00262-024-03765-8. Cancer Immunol Immunother. 2024. PMID: 38960949 Free PMC article.
A novel interleukin-2-based fusion molecule, HCW9302, differentially promotes regulatory T cell expansion to treat atherosclerosis in mice.
Zhu X, Li Q, George V, Spanoudis C, Gilkes C, Shrestha N, Liu B, Kong L, You L, Echeverri C, Li L, Wang Z, Chaturvedi P, Muniz GJ, Egan JO, Rhode PR, Wong HC. Zhu X, et al. Among authors: li l, li q. Front Immunol. 2023 Jan 25;14:1114802. doi: 10.3389/fimmu.2023.1114802. eCollection 2023. Front Immunol. 2023. PMID: 36761778 Free PMC article.
Immunotherapeutic approach to reduce senescent cells and alleviate senescence-associated secretory phenotype in mice.
Shrestha N, Chaturvedi P, Zhu X, Dee MJ, George V, Janney C, Egan JO, Liu B, Foster M, Marsala L, Wong P, Cubitt CC, Foltz JA, Tran J, Schappe T, Hsiao K, Leclerc GM, You L, Echeverri C, Spanoudis C, Carvalho A, Kanakaraj L, Gilkes C, Encalada N, Kong L, Wang M, Fang B, Wang Z, Jiao JA, Muniz GJ, Jeng EK, Valdivieso N, Li L, Deth R, Berrien-Elliott MM, Fehniger TA, Rhode PR, Wong HC. Shrestha N, et al. Among authors: li l. Aging Cell. 2023 May;22(5):e13806. doi: 10.1111/acel.13806. Epub 2023 Mar 26. Aging Cell. 2023. PMID: 36967480 Free PMC article.
Electromagnetic metamaterial agent.
Hu S, Li M, Xu J, Zhang H, Zhang S, Cui TJ, Del Hougne P, Li L. Hu S, et al. Among authors: li l. Light Sci Appl. 2025 Jan 1;14(1):12. doi: 10.1038/s41377-024-01678-w. Light Sci Appl. 2025. PMID: 39741131
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