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Page 1
Increased secretion of adipocyte-derived extracellular vesicles is associated with adipose tissue inflammation and the mobilization of excess lipid in human obesity.
Matilainen J, Berg V, Vaittinen M, Impola U, Mustonen AM, Männistö V, Malinen M, Luukkonen V, Rosso N, Turunen T, Käkelä P, Palmisano S, Arasu UT, Sihvo SP, Aaltonen N, Härkönen K, Caddeo A, Kaminska D, Pajukanta P, Kaikkonen MU, Tiribelli C, Käkelä R, Laitinen S, Pihlajamäki J, Nieminen P, Rilla K. Matilainen J, et al. Among authors: laitinen s. J Transl Med. 2024 Jul 4;22(1):623. doi: 10.1186/s12967-024-05249-w. J Transl Med. 2024. PMID: 38965596 Free PMC article.
Extracellular membrane vesicles from umbilical cord blood-derived MSC protect against ischemic acute kidney injury, a feature that is lost after inflammatory conditioning.
Kilpinen L, Impola U, Sankkila L, Ritamo I, Aatonen M, Kilpinen S, Tuimala J, Valmu L, Levijoki J, Finckenberg P, Siljander P, Kankuri E, Mervaala E, Laitinen S. Kilpinen L, et al. Among authors: laitinen s. J Extracell Vesicles. 2013 Dec 10;2. doi: 10.3402/jev.v2i0.21927. eCollection 2013. J Extracell Vesicles. 2013. PMID: 24349659 Free PMC article.
Phospholipid composition of packed red blood cells and that of extracellular vesicles show a high resemblance and stability during storage.
Laurén E, Tigistu-Sahle F, Valkonen S, Westberg M, Valkeajärvi A, Eronen J, Siljander P, Pettilä V, Käkelä R, Laitinen S, Kerkelä E. Laurén E, et al. Among authors: laitinen s. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Jan;1863(1):1-8. doi: 10.1016/j.bbalip.2017.09.012. Epub 2017 Sep 28. Biochim Biophys Acta Mol Cell Biol Lipids. 2018. PMID: 28965917
Mesenchymal Stromal Cells and Their Extracellular Vesicles Enhance the Anti-Inflammatory Phenotype of Regulatory Macrophages by Downregulating the Production of Interleukin (IL)-23 and IL-22.
Hyvärinen K, Holopainen M, Skirdenko V, Ruhanen H, Lehenkari P, Korhonen M, Käkelä R, Laitinen S, Kerkelä E. Hyvärinen K, et al. Among authors: laitinen s. Front Immunol. 2018 Apr 12;9:771. doi: 10.3389/fimmu.2018.00771. eCollection 2018. Front Immunol. 2018. PMID: 29706969 Free PMC article.
Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules.
Valkonen S, Holopainen M, Colas RA, Impola U, Dalli J, Käkelä R, Siljander PR, Laitinen S. Valkonen S, et al. Among authors: laitinen s. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Aug;1864(8):1168-1182. doi: 10.1016/j.bbalip.2019.03.011. Epub 2019 Apr 10. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 30980920
Polyunsaturated fatty acids modify the extracellular vesicle membranes and increase the production of proresolving lipid mediators of human mesenchymal stromal cells.
Holopainen M, Colas RA, Valkonen S, Tigistu-Sahle F, Hyvärinen K, Mazzacuva F, Lehenkari P, Käkelä R, Dalli J, Kerkelä E, Laitinen S. Holopainen M, et al. Among authors: laitinen s. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Oct;1864(10):1350-1362. doi: 10.1016/j.bbalip.2019.06.010. Epub 2019 Jun 15. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 31207356
228 results