Vallone B - Search Results

1

Binding of steroid substrates reveals the key to the productive transition of the cytochrome P450 OleP.

Costanzo A, Fata F, Freda I, De Sciscio ML, Gugole E, Bulfaro G, Di Renzo M, Barbizzi L, Exertier C, Parisi G, D'Abramo M, Vallone B, Savino C, Montemiglio LC. Costanzo A, et al. Among authors: vallone b. Structure. 2024 Sep 5;32(9):1465-1476.e3. doi: 10.1016/j.str.2024.06.005. Epub 2024 Jul 5. Structure. 2024. PMID: 38971159 Free article.

2

Dissecting the Cytochrome P450 OleP Substrate Specificity: Evidence for a Preferential Substrate.

Parisi G, Freda I, Exertier C, Cecchetti C, Gugole E, Cerutti G, D'Auria L, Macone A, Vallone B, Savino C, Montemiglio LC. Parisi G, et al. Among authors: vallone b. Biomolecules. 2020 Oct 6;10(10):1411. doi: 10.3390/biom10101411. Biomolecules. 2020. PMID: 33036250 Free PMC article.

3

Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics.

Montemiglio LC, Gugole E, Freda I, Exertier C, D'Auria L, Chen CG, Nardi AN, Cerutti G, Parisi G, D'Abramo M, Savino C, Vallone B. Montemiglio LC, et al. Among authors: vallone b. Biomolecules. 2021 Dec 31;12(1):55. doi: 10.3390/biom12010055. Biomolecules. 2021. PMID: 35053203 Free PMC article.

4

Effect of Salts on the Conformational Dynamics of the Cytochrome P450 OleP.

De Sciscio ML, Nardi AN, Parisi G, Bulfaro G, Costanzo A, Gugole E, Exertier C, Freda I, Savino C, Vallone B, Montemiglio LC, D'Abramo M. De Sciscio ML, et al. Among authors: vallone b. Molecules. 2023 Jan 13;28(2):832. doi: 10.3390/molecules28020832. Molecules. 2023. PMID: 36677890 Free PMC article.

5

Azole drugs trap cytochrome P450 EryK in alternative conformational states.

Montemiglio LC, Gianni S, Vallone B, Savino C. Montemiglio LC, et al. Among authors: vallone b. Biochemistry. 2010 Nov 2;49(43):9199-206. doi: 10.1021/bi101062v. Biochemistry. 2010. PMID: 20845962

6

Functional analysis and crystallographic structure of clotrimazole bound OleP, a cytochrome P450 epoxidase from Streptomyces antibioticus involved in oleandomycin biosynthesis.

Montemiglio LC, Parisi G, Scaglione A, Sciara G, Savino C, Vallone B. Montemiglio LC, et al. Among authors: vallone b. Biochim Biophys Acta. 2016 Mar;1860(3):465-75. doi: 10.1016/j.bbagen.2015.10.009. Epub 2015 Oct 22. Biochim Biophys Acta. 2016. PMID: 26475642

7

Substrate-induced conformational change in cytochrome P450 OleP.

Parisi G, Montemiglio LC, Giuffrè A, Macone A, Scaglione A, Cerutti G, Exertier C, Savino C, Vallone B. Parisi G, et al. Among authors: vallone b. FASEB J. 2019 Feb;33(2):1787-1800. doi: 10.1096/fj.201800450RR. Epub 2018 Sep 12. FASEB J. 2019. PMID: 30207799

C., Giuffre, A., Macone, A., Scaglione, A., Cerutti, G., Exertier, C., Savino, C., Vallone, B. Substrate-induced conformational change in cytochrome P450 OleP....

C., Giuffre, A., Macone, A., Scaglione, A., Cerutti, G., Exertier, C., Savino, C., Vallone, B. Substrate-induced conformationa …

8

Investigating the structural plasticity of a cytochrome P450: three-dimensional structures of P450 EryK and binding to its physiological substrate.

Savino C, Montemiglio LC, Sciara G, Miele AE, Kendrew SG, Jemth P, Gianni S, Vallone B. Savino C, et al. Among authors: vallone b. J Biol Chem. 2009 Oct 16;284(42):29170-9. doi: 10.1074/jbc.M109.003590. Epub 2009 Jul 22. J Biol Chem. 2009. PMID: 19625248 Free PMC article.

9

Insights into DNA replication: the crystal structure of DNA polymerase B1 from the archaeon Sulfolobus solfataricus.

Savino C, Federici L, Johnson KA, Vallone B, Nastopoulos V, Rossi M, Pisani FM, Tsernoglou D. Savino C, et al. Among authors: vallone b. Structure. 2004 Nov;12(11):2001-8. doi: 10.1016/j.str.2004.09.007. Structure. 2004. PMID: 15530364 Free article.

10

Proximal and distal control for ligand binding in neuroglobin: role of the CD loop and evidence for His64 gating.

Exertier C, Milazzo L, Freda I, Montemiglio LC, Scaglione A, Cerutti G, Parisi G, Anselmi M, Smulevich G, Savino C, Vallone B. Exertier C, et al. Among authors: vallone b. Sci Rep. 2019 Mar 29;9(1):5326. doi: 10.1038/s41598-019-41780-3. Sci Rep. 2019. PMID: 30926858 Free PMC article.

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