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Thyrocytes express a functional toll-like receptor 3: overexpression can be induced by viral infection and reversed by phenylmethimazole and is associated with Hashimoto's autoimmune thyroiditis.
Harii N, Lewis CJ, Vasko V, McCall K, Benavides-Peralta U, Sun X, Ringel MD, Saji M, Giuliani C, Napolitano G, Goetz DJ, Kohn LD. Harii N, et al. Mol Endocrinol. 2005 May;19(5):1231-50. doi: 10.1210/me.2004-0100. Epub 2005 Jan 20. Mol Endocrinol. 2005. PMID: 15661832
Wnt5a is expressed in murine and human atherosclerotic lesions.
Christman MA 2nd, Goetz DJ, Dickerson E, McCall KD, Lewis CJ, Benencia F, Silver MJ, Kohn LD, Malgor R. Christman MA 2nd, et al. Among authors: mccall kd. Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2864-70. doi: 10.1152/ajpheart.00982.2007. Epub 2008 May 2. Am J Physiol Heart Circ Physiol. 2008. PMID: 18456733 Free article.
Phenylmethimazole decreases Toll-like receptor 3 and noncanonical Wnt5a expression in pancreatic cancer and melanoma together with tumor cell growth and migration.
Schwartz AL, Malgor R, Dickerson E, Weeraratna AT, Slominski A, Wortsman J, Harii N, Kohn AD, Moon RT, Schwartz FL, Goetz DJ, Kohn LD, McCall KD. Schwartz AL, et al. Among authors: mccall kd. Clin Cancer Res. 2009 Jun 15;15(12):4114-22. doi: 10.1158/1078-0432.CCR-09-0005. Epub 2009 May 26. Clin Cancer Res. 2009. PMID: 19470740 Free PMC article.
A sandwich ELISA for the detection of Wnt5a.
Kummitha CM, Mayle KM, Christman MA 2nd, Deosarkar SP, Schwartz AL, McCall KD, Kohn LD, Malgor R, Goetz DJ. Kummitha CM, et al. Among authors: mccall kd. J Immunol Methods. 2010 Jan 31;352(1-2):38-44. doi: 10.1016/j.jim.2009.11.005. Epub 2009 Nov 15. J Immunol Methods. 2010. PMID: 19919840 Free PMC article.
Wnt5a, TLR2 and TLR4 are elevated in advanced human atherosclerotic lesions.
Malgor R, Bhatt PM, Connolly BA, Jacoby DL, Feldmann KJ, Silver MJ, Nakazawa M, McCall KD, Goetz DJ. Malgor R, et al. Among authors: mccall kd. Inflamm Res. 2014 Apr;63(4):277-85. doi: 10.1007/s00011-013-0697-x. Epub 2013 Dec 18. Inflamm Res. 2014. PMID: 24346141 Free PMC article.
Simple modifications to methimazole that enhance its inhibitory effect on tumor necrosis factor-α-induced vascular cell adhesion molecule-1 expression by human endothelial cells.
Alapati A, Deosarkar SP, Lanier OL, Qi C, Carlson GE, Burdick MM, Schwartz FL, McCall KD, Bergmeier SC, Goetz DJ. Alapati A, et al. Among authors: mccall kd. Eur J Pharmacol. 2015 Mar 15;751:59-66. doi: 10.1016/j.ejphar.2015.01.032. Epub 2015 Jan 29. Eur J Pharmacol. 2015. PMID: 25641748 Free PMC article.
36 results