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Page 1
NRF2-dependent regulation of the prostacyclin receptor PTGIR drives CD8 T cell exhaustion.
Dahabieh MS, DeCamp LM, Oswald BM, Kitchen-Goosen SM, Fu Z, Vos M, Compton SE, Longo J, Williams KS, Ellis AE, Johnson A, Sodiya I, Vincent M, Lee H, Sheldon RD, Krawczyk CM, Yao C, Wu T, Jones RG. Dahabieh MS, et al. Among authors: ellis ae. bioRxiv [Preprint]. 2024 Jun 28:2024.06.23.600279. doi: 10.1101/2024.06.23.600279. bioRxiv. 2024. PMID: 38979360 Free PMC article. Preprint.
Prior metabolite extraction fully preserves RNAseq quality and enables integrative multi-'omics analysis of the liver metabolic response to viral infection.
Madaj ZB, Dahabieh MS, Kamalumpundi V, Muhire B, Pettinga J, Siwicki RA, Ellis AE, Isaguirre C, Escobar Galvis ML, DeCamp L, Jones RG, Givan SA, Adams M, Sheldon RD. Madaj ZB, et al. Among authors: ellis ae. RNA Biol. 2023 Jan;20(1):186-197. doi: 10.1080/15476286.2023.2204586. RNA Biol. 2023. PMID: 37095747 Free PMC article.
Lipid availability influences ferroptosis sensitivity in cancer cells by regulating polyunsaturated fatty acid trafficking.
Sokol KH, Lee CJ, Rogers TJ, Waldhart A, Ellis AE, Madireddy S, Daniels SR, Ye X, Olesnavich M, Johnson A, Furness BR, Sheldon RD, Lien EC. Sokol KH, et al. Among authors: ellis ae. bioRxiv [Preprint]. 2024 May 9:2024.05.06.592780. doi: 10.1101/2024.05.06.592780. bioRxiv. 2024. Update in: Cell Chem Biol. 2024 Oct 14:S2451-9456(24)00404-5. doi: 10.1016/j.chembiol.2024.09.008 PMID: 38766165 Free PMC article. Updated. Preprint.
A diverse proteome is present and enzymatically active in metabolite extracts.
House RRJ, Soper-Hopper MT, Vincent MP, Ellis AE, Capan CD, Madaj ZB, Wolfrum E, Isaguirre CN, Castello CD, Johnson AB, Escobar Galvis ML, Williams KS, Lee H, Sheldon RD. House RRJ, et al. Among authors: ellis ae. Nat Commun. 2024 Jul 10;15(1):5796. doi: 10.1038/s41467-024-50128-z. Nat Commun. 2024. PMID: 38987243 Free PMC article.
Lipid availability influences ferroptosis sensitivity in cancer cells by regulating polyunsaturated fatty acid trafficking.
Sokol KH, Lee CJ, Rogers TJ, Waldhart A, Ellis AE, Madireddy S, Daniels SR, House RRJ, Ye X, Olesnavich M, Johnson A, Furness BR, Sheldon RD, Lien EC. Sokol KH, et al. Among authors: ellis ae. Cell Chem Biol. 2024 Oct 14:S2451-9456(24)00404-5. doi: 10.1016/j.chembiol.2024.09.008. Online ahead of print. Cell Chem Biol. 2024. PMID: 39442523 Free article.
Glucose-dependent glycosphingolipid biosynthesis fuels CD8+ T cell function and tumor control.
Longo J, DeCamp LM, Oswald BM, Teis R, Reyes-Oliveras A, Dahabieh MS, Ellis AE, Vincent MP, Damico H, Gallik KL, Compton SE, Capan CD, Williams KS, Esquibel CR, Madaj ZB, Lee H, Roy DG, Krawczyk CM, Haab BB, Sheldon RD, Jones RG. Longo J, et al. Among authors: ellis ae. bioRxiv [Preprint]. 2024 Oct 14:2024.10.10.617261. doi: 10.1101/2024.10.10.617261. bioRxiv. 2024. PMID: 39464161 Free PMC article. Preprint.
Dietary Restriction Enhances CD8+ T Cell Ketolysis to Limit Exhaustion and Boost Anti-Tumor Immunity.
Oswald BM, DeCamp LM, Longo J, Dahabieh MS, Bunda N, Ma S, Watson MJ, Sheldon RD, Vincent MP, Johnson BK, Ellis AE, Soper-Hopper MT, Isaguirre CN, Shen H, Williams KS, Crawford PA, Kaech S, Jang HJ, Krawczyk CM, Jones RG. Oswald BM, et al. Among authors: ellis ae. bioRxiv [Preprint]. 2024 Nov 15:2024.11.14.621733. doi: 10.1101/2024.11.14.621733. bioRxiv. 2024. PMID: 39605550 Free PMC article. Preprint.
Nutrient-driven histone code determines exhausted CD8+ T cell fates.
Ma S, Dahabieh MS, Mann TH, Zhao S, McDonald B, Song WS, Chung HK, Farsakoglu Y, Garcia-Rivera L, Hoffmann FA, Xu S, Du VY, Chen D, Furgiuele J, LaPorta M, Jacobs E, DeCamp LM, Oswald BM, Sheldon RD, Ellis AE, Liu L, He P, Wang Y, Jang C, Jones RG, Kaech SM. Ma S, et al. Among authors: ellis ae. Science. 2024 Dec 12:eadj3020. doi: 10.1126/science.adj3020. Online ahead of print. Science. 2024. PMID: 39666821
163 results