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Contribution of Noncovalent Recognition and Reactivity to the Optimization of Covalent Inhibitors: A Case Study on KRasG12C.
Péczka N, Ranđelović I, Orgován Z, Csorba N, Egyed A, Petri L, Ábrányi-Balogh P, Gadanecz M, Perczel A, Tóvári J, Schlosser G, Takács T, Mihalovits LM, Ferenczy GG, Buday L, Keserű GM. Péczka N, et al. Among authors: takacs t. ACS Chem Biol. 2024 Aug 16;19(8):1743-1756. doi: 10.1021/acschembio.4c00217. Epub 2024 Jul 11. ACS Chem Biol. 2024. PMID: 38991015 Free PMC article.
Mapping protein binding sites by photoreactive fragment pharmacophores.
Ábrányi-Balogh P, Bajusz D, Orgován Z, Keeley AB, Petri L, Péczka N, Szalai TV, Pálfy G, Gadanecz M, Grant EK, Imre T, Takács T, Ranđelović I, Baranyi M, Marton A, Schlosser G, Ashraf QF, de Araujo ED, Karancsi T, Buday L, Tóvári J, Perczel A, Bush JT, Keserű GM. Ábrányi-Balogh P, et al. Among authors: takacs t. Commun Chem. 2024 Jul 31;7(1):168. doi: 10.1038/s42004-024-01252-w. Commun Chem. 2024. PMID: 39085342 Free PMC article.
Target-Templated Construction of Functional Proteomimetics Using Photo-Foldamer Libraries.
Wéber E, Ábrányi-Balogh P, Nagymihály B, Menyhárd DK, Péczka N, Gadanecz M, Schlosser G, Orgován Z, Bogár F, Bajusz D, Kecskeméti G, Szabó Z, Bartus É, Tököli A, Tóth GK, Szalai TV, Takács T, de Araujo E, Buday L, Perczel A, Martinek TA, Keserű GM. Wéber E, et al. Among authors: takacs t. Angew Chem Int Ed Engl. 2025 Jan 10;64(2):e202410435. doi: 10.1002/anie.202410435. Epub 2024 Nov 6. Angew Chem Int Ed Engl. 2025. PMID: 39329252
Heavy metals in cigarette smoke strongly inhibit pancreatic ductal function and promote development of chronic pancreatitis.
Pallagi P, Tóth E, Görög M, Venglovecz V, Madácsy T, Varga Á, Molnár T, Papp N, Szabó V, Kúthy-Sutus E, Molnár R, Ördög A, Borka K, Schnúr A, Kéri A, Kajner G, Csekő K, Ritter E, Csupor D, Helyes Z, Galbács G, Szentesi A, Czakó L, Rakonczay Z, Takács T, Maléth J, Hegyi P. Pallagi P, et al. Among authors: takacs t. Clin Transl Med. 2024 Jun;14(6):e1733. doi: 10.1002/ctm2.1733. Clin Transl Med. 2024. PMID: 38877637 Free PMC article.
231 results