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Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease.
Watabe-Rudolph M, Song Z, Lausser L, Schnack C, Begus-Nahrmann Y, Scheithauer MO, Rettinger G, Otto M, Tumani H, Thal DR, Attems J, Jellinger KA, Kestler HA, von Arnim CA, Rudolph KL. Watabe-Rudolph M, et al. Among authors: thal dr. Neurology. 2012 Feb 21;78(8):569-77. doi: 10.1212/WNL.0b013e318247caa1. Epub 2012 Feb 8. Neurology. 2012. PMID: 22323746
Limited role of free TDP-43 as a diagnostic tool in neurodegenerative diseases.
Feneberg E, Steinacker P, Lehnert S, Schneider A, Walther P, Thal DR, Linsenmeier M, Ludolph AC, Otto M. Feneberg E, et al. Among authors: thal dr. Amyotroph Lateral Scler Frontotemporal Degener. 2014 Sep;15(5-6):351-6. doi: 10.3109/21678421.2014.905606. Epub 2014 May 16. Amyotroph Lateral Scler Frontotemporal Degener. 2014. PMID: 24834468
Different neuroinflammatory profile in amyotrophic lateral sclerosis and frontotemporal dementia is linked to the clinical phase.
Oeckl P, Weydt P, Steinacker P, Anderl-Straub S, Nordin F, Volk AE, Diehl-Schmid J, Andersen PM, Kornhuber J, Danek A, Fassbender K, Fliessbach K; German Consortium for Frontotemporal Lobar Degeneration; Jahn H, Lauer M, Müller K, Knehr A, Prudlo J, Schneider A, Thal DR, Yilmazer-Hanke D, Weishaupt JH, Ludolph AC, Otto M. Oeckl P, et al. Among authors: thal dr. J Neurol Neurosurg Psychiatry. 2019 Jan;90(1):4-10. doi: 10.1136/jnnp-2018-318868. Epub 2018 Sep 17. J Neurol Neurosurg Psychiatry. 2019. PMID: 30224549
Different aspects of Alzheimer's disease-related amyloid β-peptide pathology and their relationship to amyloid positron emission tomography imaging and dementia.
Thal DR, Ronisz A, Tousseyn T, Rijal Upadhaya A, Balakrishnan K, Vandenberghe R, Vandenbulcke M, von Arnim CAF, Otto M, Beach TG, Lilja J, Heurling K, Chakrabarty A, Ismail A, Buckley C, Smith APL, Kumar S, Farrar G, Walter J. Thal DR, et al. Acta Neuropathol Commun. 2019 Nov 14;7(1):178. doi: 10.1186/s40478-019-0837-9. Acta Neuropathol Commun. 2019. PMID: 31727169 Free PMC article. Clinical Trial.
248 results